IsisCB Explore

Article ID: CBB947878756

From Organ Culture to the New 3D Organotypic Culture Systems: Conceptual Pathways (2020)

Physis: Rivista Internazionale di Storia della Scienza
Volume: 55
Pages: 203-222
Publication date: 2020
Language: English

Outside Links

WorldCat

Google Scholar

JSTOR

Tissue culture, or explantation technique, deeply renewed the experimental method in biology and medicine and the style of observation of life-sustaining processes in multicellular organisms. Lately, the historiography of tissue culture has focused mostly on cell culture, because of its crucial role in the molecularization of biology. The recent revival of 3D organotypic culture, driven by the synergy between tissue microengineering, cell and stem cell biology, fosters a reappraisal of the conceptual, and not only technical, legacy of the older organotypic experimental tradition within the long history of the tissue culture community. Crucial in this respect is the emergence about the 1950s of the notion of microenvironment, which has lately become a cornerstone of the “three-dimensional thinking” paradigm promoted by the new generation of organ culturists committed to a multilevel extension of Systems Biology research.

...More

Citation URI

data.isiscb.org/p/isis/citation/CBB947878756

This citation is part of the Isis database.

Citations Indexes

Similar Citations

Article Erez Braun; Shimon Marom; (2015)
Universality, complexity and the praxis of biology: Two case studies (/p/isis/citation/CBB948011358/)

Article Creager, Angela N. H.; (2013)
Timescapes of Radioactive Tracers in Biochemistry and Ecology (/p/isis/citation/CBB001211940/)

Chapter Rheinberger, Hans-Jörg; (2008)
Intersections: Some Thoughts on Instruments and Objects in the Experimental Context of the Life Sciences (/p/isis/citation/CBB000831231/)

Article Gabriele Gramelsberger; (2018)
Continuous Culture Techniques as Simulators for Standard Cells: Jacques Monod’s, Aron Novick’s and Leo Szilard’s Quantitative Approach to Microbiology (/p/isis/citation/CBB125915386/)

Article Wolpin, Stewart; (Spring 2010)
Welcome To The Future—And It's In 3-D (/p/isis/citation/CBB458658158/)

Book Skloot, Rebecca; (2010)
The immortal life of Henrietta Lacks (/p/isis/citation/CBB438514916/)

Article Tara Suri; (2022)
Between Simians and Cell Lines: Rhesus Monkeys, Polio Research, and the Geopolitics of Tissue Culture (1934–1954) (/p/isis/citation/CBB316653885/)

Book Wilson, Duncan; (2011)
Tissue Culture in Science and Society: The Public Life of a Biological Technique in Twentieth Century Britain (/p/isis/citation/CBB001250994/)

Article Thomas Kirchhoff; (2020)
The Myth of Frederic Clements’s Mutualistic Organicism, or: On the Necessity to Distinguish Different Concepts of Organicism (/p/isis/citation/CBB621023099/)

Book Michel Morange; (2020)
The Black Box of Biology: A History of the Molecular Revolution (/p/isis/citation/CBB035364586/)

Article Janina Wellmann; (2018)
Model and Movement: Studying Cell Movement in Early Morphogenesis, 1900 to the Present (/p/isis/citation/CBB034220227/)

Article Green, Sara; Wolkenhauer, Olaf; (2013)
Tracing Organizing Principles: Learning from the History of Systems Biology (/p/isis/citation/CBB001420760/)

Article Bechtel, William; (2010)
The Cell: Locus or Object of Inquiry? (/p/isis/citation/CBB001023957/)

Chapter Callebaut, Werner; Müller, Gerd B.; Newman, Stuart A.; (2007)
The Organismic Systems Approach: Evo-Devo and the Streamlining of the Naturalistic Agenda (/p/isis/citation/CBB001213667/)

Chapter Roberto Serra; (2015)
Proprietà generiche nei sistemi complessi (/p/isis/citation/CBB320748884/)

Article Manfred Drack; (2009)
Towards the System Heuristics of Paul Weiss (/p/isis/citation/CBB262240198/)

Article Gall, Yasha M.; Konashev, Mikhail B.; (2001)
The Discovery of Gramicidin S: The Intellectual Transformation of G. F. Gause from Biologist to Researcher of Antibiotics and on Its Meaning for the Fate of Russian Genetics (/p/isis/citation/CBB000770067/)

Chapter Ariane Dröscher; (2015)
Microscopic truths: the multiple realities of the Golgi apparatus (/p/isis/citation/CBB973703234/)

Article Maria Carla Garbarino; Paolo Mazzarello; (2022)
Giuseppe Levi e Rita Levi-Montalcini: Il lungo cammino di una “biologia dinamica”, dall’embriologia alle moderne neuroscienze (/p/isis/citation/CBB948356892/)

Article Heggie, Vanessa; (2013)
Experimental Physiology, Everest and Oxygen: From the Ghastly Kitchens to the Gasping Lung (/p/isis/citation/CBB001252461/)