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Book ID: CBB444510423

Model Behavior: Animal Experiments, Complexity, and the Genetics of Psychiatric Disorders (2018)

Nelson, Nicole C. (Author)

University of Chicago Press
Publication date: 2018
Language: English

ISBN: 9780226545929

Publication Date: 2018
Physical Details: 272 pp.

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Mental disorders and diseases Psychiatry Laboratories Behaviorism Behavioral sciences Animal experimentation 21st century

Mice are used as model organisms across a wide range of fields in science today—but it is far from obvious how studying a mouse in a maze can help us understand human problems like alcoholism or anxiety. How do scientists convince funders, fellow scientists, the general public, and even themselves that animal experiments are a good way of producing knowledge about the genetics of human behavior? In Model Behavior, Nicole C. Nelson takes us inside an animal behavior genetics laboratory to examine how scientists create and manage the foundational knowledge of their field. Behavior genetics is a particularly challenging field for making a clear-cut case that mouse experiments work, because researchers believe that both the phenomena they are studying and the animal models they are using are complex. These assumptions of complexity change the nature of what laboratory work produces. Whereas historical and ethnographic studies traditionally portray the laboratory as a place where scientists control, simplify, and stabilize nature in the service of producing durable facts, the laboratory that emerges from Nelson’s extensive interviews and fieldwork is a place where stable findings are always just out of reach. The ongoing work of managing precarious experimental systems means that researchers learn as much—if not more—about the impact of the environment on behavior as they do about genetics. Model Behavior offers a compelling portrait of life in a twenty-first-century laboratory, where partial, provisional answers to complex scientific questions are increasingly the norm.

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Reviewed By

Review Rachel A. Ankeny (2020) Review of "Model Behavior: Animal Experiments, Complexity, and the Genetics of Psychiatric Disorders". Journal of the History of Biology (pp. 657-658). unapi

Review Nicole C. Nelson (2020) Review of "Model Behavior: Animal Experiments, Complexity, and the Genetics of Psychiatric Disorders". Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences (p. 101249). unapi

Review Eva Haifa Giraud (2020) Review of "Model Behavior: Animal Experiments, Complexity, and the Genetics of Psychiatric Disorders". Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences (p. 101249). unapi

Review Wayne Hall (2020) Review of "Model Behavior: Animal Experiments, Complexity, and the Genetics of Psychiatric Disorders". Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences (p. 101249). unapi

Review Jacqueline Sullivan (2020) Review of "Model Behavior: Animal Experiments, Complexity, and the Genetics of Psychiatric Disorders". Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences (p. 101249). unapi

Review Tarquin Holmes (2020) Review of "Model Behavior: Animal Experiments, Complexity, and the Genetics of Psychiatric Disorders". British Journal for the History of Science (pp. 279-280). unapi

Review Rachel Mason Dentinger (2019) Review of "Model Behavior: Animal Experiments, Complexity, and the Genetics of Psychiatric Disorders". Journal of the History of Medicine and Allied Sciences (pp. 484-486). unapi

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