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Article ID: CBB213481216

Bone grafting in the pre-antiseptic era (historical review): Creation of the first theories related to bone grafting: 1860-1880 (2023)

Alexander Pankratov (Author)
Astemir Shaikhaliev (Author)

Medicina Historica
Volume: 7
Issue: 1
Pages: 1-7
Publication date: 2023
Language: English

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This article examines the period of formation of the theoretical foundations of bone plastic surgery and the ideas about bone regeneration in general, which predetermined the development of this branch of medical science in the following decades. The work covers the period from L. Ollier’s experimental work to W.Macewen’s operation (1881). At the time, there was a lively debate in the scientific literature regarding the fate of the transplanted bone fragment and the sources of bone tissue regeneration. Microscopic techniques have been used for the first time to study this process, albeit in a limited number of observations. The article analyses the arguments of each of the parties involved in the debate. Although no general concept was devel-oped at that time, the accumulated facts formed the basis for subsequent clinical experiments made possible by the introduction of an antiseptic approach to surgical practice.

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