Article ID: CBB882048061

Clinical Diagnosis and Cancer Probe: A History of Unity and Mass Migration (2023)

unapi

In 1964 the mobility of Spanish biochemists from Europe to the United States resulted in a simple method to estimate the molecular weight of proteins (SDS-Page). Five years before, the idea that modifications of DNA-histones binding stopped RNA synthesis came at the hand of Vincent G. Allfrey in 1959. The discovery showed crucial and its interaction with the notable Spanish research program in US provided a new direction for the design of cancer diagnostic probes. In 1985, Manuel Perucho unified this view with the relevance of the polymerase that synthesizes DNA and RNA, in a method to detect single point mutations in oncogenic genes. It is expected to expose here the history of this useful approach who sought to use histone modifications in cancer clinical practice.

...More
Citation URI
https://data.isiscb.org/isis/citation/CBB882048061/

Similar Citations

Article Enrique Wulff; (2023)
Clinical Diagnosis and Cancer Probe: A History of Unity and Mass Migration

Article Seeman, Philip; (2014)
Discovery of Why Acute Lymphoblastic Leukaemia Cells Are Killed by Asparaginase: Adventures of a Young Post-Doctoral Student, Bertha K Madras

Article Jack S. Cohen; Peter F. Daly; (2022)
History of Research on Phospholipid Metabolism and Applications to the Detection, Diagnosis, and Treatment of Cancer

Article Ginsberg, Judah; (2011)
Breaking the Code

Article Onaga, Lisa A.; (2014)
Ray Wu as Fifth Business: Deconstructing Collective Memory in the History of DNA Sequencing

Chapter Roberto Taramelli; (2016)
Una nuova visione del cancro attraverso le lenti della dinamica dei sistemi

Article Jack S. Cohen; (2021)
History of Research on Antisense Oligonucleotide Analogs

Article Costa, Rui Manuel Pinto; (2012)
Entre a teoria parasitária e a oncologia experimental: uma proposta de sistematização da ciência oncológica em Portugal, 1889--1945

Article Stark, Laura; Campbell, Nancy D.; (2014)
Stowaways in the History of Science: The Case of Simian Virus 40 and Clinical Research on Federal Prisoners at the US National Institutes of Health, 1960

Book Ludmerer, Kenneth M.; (2015)
Let Me Heal: The Opportunity to Preserve Excellence in American Medicine

Book Perlman, Robert L; (2013)
Evolution and Medicine

Article Cantor, David; (2006)
The Frustrations of Families: Henry Lynch, Heredity, and Cancer Control, 1962--1975

Book Skloot, Rebecca; (2010)
The immortal life of Henrietta Lacks

Book Almond, Peter R.; (2013)
Cobalt Blues: The Story of Leonard Grimmett, the Man behind the First Cobalt-60 Unit in the United States

Article Robin W Scheffler; Natalie B Aviles; (April 2022)
State planning, cancer vaccine infrastructure, and the origins of the oncogene theory

Article Teixeira, Luiz Antonio; (2010)
O controle do câncer no Brasil na primeira metade do século XX

Article Krueger, Gretchen; (2004)
Death Be Not Proud: Children, Families, and Cancer in Postwar America

Article Cantor, David; (2007)
Introduction: Cancer Control and Prevention in the Twentieth Century

Book Löwy, Ilana; (2009)
Preventive Strikes: Women, Precancer, and Prophylactic Surgery

Thesis Romano, Sally Dunne; (2006)
The Dark Side of the Sun: Skin Cancer, Sunscreen, and Risk in Twentieth-Century America

Authors & Contributors
Cantor, David
Cohen, Jack S.
Almond, Peter R.
Campbell, Nancy D.
Costa, Rui Manuel Pinto
Krueger, Gretchen Marie
Journals
Bulletin of the History of Medicine
História, Ciências, Saúde---Manguinhos
Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences
Substantia: An International Journal of the History of Chemistry
Chemical Heritage
Journal of Medical Biography
Publishers
Oxford University Press
Yale University
Crown Publishers
Johns Hopkins University Press
Springer
Concepts
Cancer; tumors
Medicine
Genetics
Biochemistry
Therapeutic practice; therapy; treatment
Clinical medicine
People
Grimmett, Leonard George
Lynch, Henry T.
Madras, Bertha K.
Nirenberg, Marshall Warren
Wu, Ray
Anthony Morris, J.
Time Periods
20th century
21st century
19th century
20th century, late
Places
United States
Great Britain
Brazil
Mexico
China
France
Institutions
Johns Hopkins University (Baltimore, Md.)
National Cancer Institute (U.S.)
United States. National Institute of Health
Comments

Be the first to comment!

{{ comment.created_by.username }} on {{ comment.created_on | date:'medium' }}

Log in or register to comment