Article ID: CBB786661245

CCP4 Software Suite: historia, evolución, contenido, retos y perspectivas de futuro (2015)

unapi

ABSTRACT Collaborative Computational Project Number 4 (CCP4) in Protein Crystallography is a public resource for producing and supporting a world-leading, integrated Suite of programs that allows researchers to determine macromolecular structures by X-ray crystallography, and other biophysical techniques. CCP4 supports the widest possible researcher community, embracing academic, not for profit, and for profit research. The primary aims of CCP4 include development and support of the development of cutting edge approaches to experimental determination and analysis of protein structure, with integration of them into the suite for worldwide dissemination. In addition, CCP4 plays an important role in the education and training of scientists in experimental structural biology. In this paper, we overview CCP4’s 35-year long history and (technical) milestones of its evolution. We will also consider how a particular structure of CCP4 Suite and Collaboration has emerged, its main functionality, current state and plans for future. RESUMEN “Collaborative Computational Project Number 4 (CCP4)” en Cristalografía de Proteínas es un recurso público líder mundial, encaminado a producir y mantener un conjunto integrado de programas que permite a los investigadores determinar estructuras macromoleculares mediante cristalografía de rayos-X, así como por otras técnicas biofísicas. CCP4 va dirigido a la más amplia comunidad científica posible, abarcando investigaciones en el ámbito académico, tanto sin ánimo de lucro como con él. Sus objetivos principales incluyen el desarrollo y soporte de metodologías punteras para la determinación y análisis de estructuras de proteínas, integradas en un conjunto bien definido para facilitar su fácil difusión mundial. Además, CCP4 juega un papel importante en la formación y entrenamiento de científicos en biología estructural experimental. En este artículo, ofreceré una visión de conjunto de la larga historia e hitos técnicos de CCP4 (35 años) y consideraré cómo ha surgido la particular estructura colaborativa de CCP4, sus características más notables, estado actual y perspectivas futuras.

...More
Citation URI
https://data.isiscb.org/isis/citation/CBB786661245/

Similar Citations

Article Pavel V. Afonine; Alexandre Urzhumtsev; Paul D. Adams; (2015)
Refinamiento de estructuras macromoleculares cristalográficas (/isis/citation/CBB688998316/)

Article Guillermo Montoya; (2015)
De la Cristalografía a la biología estructural, un siglo de descubrimientos (/isis/citation/CBB716141674/)

Article Enrico A. Stura; (2015)
Cristalización de proteínas en el diseño de fármacos en los últimos 50 años (/isis/citation/CBB320500524/)

Article Julia Sanz-Aparicio; (2015)
El legado de las mujeres a la cristalografía (/isis/citation/CBB030122133/)

Article Celerino Abad-Zapatero; (2015)
Celebrando la cristalografía macromolecular: una perspectiva personal (/isis/citation/CBB700623394/)

Article Black, Suzanne; (2005)
Domesticating the Crystal: Sir Lawrence Bragg and the Aesthetics of “X-ray Analysis” (/isis/citation/CBB000850143/)

Article Trevor W. Hambley; Ian D. Rae; (2022)
Hans Charles Freeman 1929–2008 (/isis/citation/CBB450605743/)

Article Hall, Kersten T.; (2011)
William Astbury and the Biological Significance of Nucleic Acids, 1938--1951 (/isis/citation/CBB001023996/)

Article Perutz, M.F.; (1990)
How Lawrence Bragg invented X-ray analysis (/isis/citation/CBB000030843/)

Book André, Authier; (2013)
Early Days of X-Ray Crystallography (/isis/citation/CBB001500387/)

Book Hunter, Graeme K.; (2004)
Light is a Messenger: The Life and Science of William Lawrence Bragg (/isis/citation/CBB000550514/)

Article Gibbons, Michelle G.; (2012)
Reassessing Discovery: Rosalind Franklin, Scientific Visualization, and the Structure of DNA (/isis/citation/CBB001210576/)

Article Creager, Angela N. H.; Morgan, Gregory J.; (2008)
After the Double Helix: Rosalind Franklin's Research on Tobacco mosaic virus (/isis/citation/CBB000850403/)

Article Scheffler, Robin Wolfe; (2009)
Interests and Instrument: A Micro-History of Object Wh.3469 (X-Ray Powder Diffraction Camera, ca. 1940) (/isis/citation/CBB000932512/)

Article Kersten Hall; (2021)
Florence Bell—the ‘Housewife’ with x-ray vision (/isis/citation/CBB196845423/)

Article Root-Bernstein, Robert Scott; (2007)
Dorothy Crowfoot Hodgkin: Structure as Art (/isis/citation/CBB000831478/)

Article Ramaseshan, S.; (1996)
Dorothy Hodgkin and the Indian connection (/isis/citation/CBB000068184/)

Chapter Paoloni, Leonello; Parente, Leticia T.S.; (1988)
Forma cristallina e struttura molecolare: La fase di transizione e la vicenda di William Barlow (1845-1934) (/isis/citation/CBB000035816/)

Authors & Contributors
Hall, Kersten T.
Stura, Enrico A.
Sanz-Aparicio, Julia
Adams, Paul D.
Urzhumtsev, Alexandre
Abad-Zapatero, Celerino
Journals
Arbor: Ciencia, Pensamiento y Cultura
Notes and Records: The Royal Society Journal of the History of Science
Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences
Studies in History and Philosophy of Science
Proceedings of the Royal Institution of Great Britain
Philosophy of Science
Publishers
Oxford University Press
International Union of Crystallography
Concepts
X-ray crystallography
Crystallography
Physics
Chemistry
Molecular biology
Biology
People
Bragg, William Lawrence
Hodgkin, Dorothy Crowfoot
Franklin, Rosalind
Bell, Florence
Freeman, Hans Charles
Watson, James Dewey
Time Periods
20th century
20th century, early
21st century
20th century, late
19th century
18th century
Places
Spain
Australia
Great Britain
Institutions
University of Sydney
University of Manchester
Cambridge University
California Institute of Technology
Comments

Be the first to comment!

{{ comment.created_by.username }} on {{ comment.created_on | date:'medium' }}

Log in or register to comment