Article ID: CBB782035686

The Holy Basil (Ocimum sanctum L.) and its Genome (2016)

unapi

Ocimum sanctum L. (O. tenuiflorum) is popular in India as “Holy basil”. It is not only designated as sacred basil but is also used as an important ingredient in Indian and some international traditional medicinal systems. There are many theories about the origin of “Tulsi” in ancient Hindi scripts. This herb is a repository of medicinal compounds and thus is also used in treatment of various diseases and disorders, but the validation of phytomolecules with differential therapeutic activities is still a challenge. Approximately, 80% of the patents on Ocimum sp. are on the chemical extracts or the utility of plant parts with main focus on essential oil components. Thus, an effort towards recognition of full metabolic potential of this sacred herb, sequencing of the whole nuclear and chloroplast genomes was performed. The data generated was obtained by combining the sequence reads from 4 libraries of three NGS platforms. This data resulted in a saturated genome draft assembly of about 386 Mb. Pathway analysis from the data indicated the dominance of phenylpropanoids in O. sanctum. Comparison of the available genes and the chemical compounds in O. sanctum and its nearest neighbor Salvia miltiorrhiza, revealed the prospects of discovering new active molecules. This information generated will help in providing new insights relating to the medicinal nature of the metabolites synthesized in the plant.

...More
Citation URI
https://data.isiscb.org/isis/citation/CBB782035686/

Similar Citations

Article Fontes da Costa, Palmira; Nobre de Carvalho, Teresa; (2013)
Entre Oriente y Occidente: Los Coloquios de García de Orta y la Circulación del Conocimiento Médico en el Siglo XVI (/isis/citation/CBB001450457/)

Article Dwivedi, Dhananjay Vasudeo; (2012)
Bilva in Indian Tradition (/isis/citation/CBB001200135/)

Article Panda, Ashok Kumar; (2010)
Tracing Historical Perspective of Cordyceps Sinensis----An Aphrodisiac in Sikkim Himālaya (/isis/citation/CBB001024274/)

Article Shah, N. C.; (2015)
Soma, an Enigmatic, Mysterious Plant of the Vedic Aryas: An Appraisal (/isis/citation/CBB001551739/)

Article Paula Arantes Botelho Briglia Habib; Robert Wegner; (2014)
De plantas y hombres: cómo los genetistas se vincularon a la eugenesia en Brasil (un estudio de caso, 1929-1938) (/isis/citation/CBB713894451/)

Thesis Fulton, Theresa Marie; (2002)
Changing Science: A History of Plant Genomics in the United States (/isis/citation/CBB001562449/)

Article Santesmases, María Jesús; (2013)
The Biological Landscape of Polyploidy: Chromosomes under Glass in the 1950s (/isis/citation/CBB001211941/)

Article Coesèl, Marga; Zevenhuizen, Erik; (2000)
Op heterdaad betrapt? Hugo de Vries en zijn houding tegenover vrouwen in de wetenschap (/isis/citation/CBB000110510/)

Chapter Rheinberger, Hans-Jörg; (2003)
Carl Correns' Experiments with Pisum, 1896--1899 (/isis/citation/CBB000330789/)

Book Jennifer A. Jordan; (2015)
Edible Memory: The Lure of Heirloom Tomatoes and Other Forgotten Foods (/isis/citation/CBB989406824/)

Book Ruse, Michael; Richards, Robert J.; (2008)
The Cambridge Companion to the Origin of Species (/isis/citation/CBB000951129/)

Article Köhler, Piotr; (2011)
Botany and Lysenkoism in Poland (/isis/citation/CBB001220380/)

Article Eduard I. Kolchinsky; (2017)
Nikolaĭ I. Vavilov in the Realm of Historical and Scientific Discussions (/isis/citation/CBB711789477/)

Article Endersby, Jim; (2013)
Mutant Utopias: Evening Primroses and Imagined Futures in Early Twentieth-Century America (/isis/citation/CBB001321212/)

Article Argueta, Arturo; Argueta, Quetzal; (2011)
Vavilov, A Soviet Darwinist in Mexico (/isis/citation/CBB001220382/)

Authors & Contributors
Ignacio García-Pereda
Pérez de la Vega, Marcelino
Tanghe, Koen B.
Kolchinsky, Eduard I.
Zevenhuizen, Erik J. A.
Wegner, Robert
Journals
Indian Journal of History of Science
Istoriko-Biologicheskie Issledovaniia
Asclepio: Archivo Iberoamericano de Historia de la Medicina
Journal of Asian Studies
Isis: International Review Devoted to the History of Science and Its Cultural Influences
History of Science
Publishers
University of Chicago Press
Cambridge University Press
Cornell University
Concepts
Botany
Genetics
India, civilization and culture
Biology
Science and culture
Cross-cultural interaction; cultural influence
People
Lysenko, Trofim Denisovich
Vries, Hugo Marie de
Kehl, Renato
Natividade, Joaquim Vieira
Rheinberger, Hans-Jörg
Vavilov, Nikolai Ivanovich
Time Periods
20th century
19th century
20th century, early
Ancient
20th century, late
16th century
Places
India
United States
Russia
Portugal
Poland
Soviet Union
Comments

Be the first to comment!

{{ comment.created_by.username }} on {{ comment.created_on | date:'medium' }}

Log in or register to comment