Andrej Dobovišek (Author)
Marko Vitas (Author)
Explaining the emergence of life is perhaps central and the most challenging question in modern science. Within this area of research, the emergence and evolution of the genetic code is supposed to be a critical transition in the evolution of modern organisms. The canonical genetic code is one of the most dominant aspects of life on this planet, and thus studying its origin is critical to understanding the evolution of life, including life’s emergence. In this sense it is possible to view the ribosome as a digital-to-analogue information converter. Why the translation apparatus evolved, is one of the enduring mysteries of molecular biology. Assuming the hypothesis that during the emergence of life evolution had to first involve autocatalytic systems, which only subsequently acquired the capacity of genetic heredity, in the present article we discuss some aspects and causes of the possible emergence of digital, discrete information arising from analogue information realized in the intra- and inter-molecular interactions throughout molecular evolution. How such reverse translation was achieved at a molecular level is still unclear. The results of such debates and investigations might shift current biological paradigms and might also have a momentous significance for modern philosophy in understanding our place in the universe.
...More
Book
Wenkel, Simone;
Deichmann, Ute;
(2007)
Max Delbrück and Cologne: An Early Chapter of German Molecular Biology
(/isis/citation/CBB000830131/)
Thesis
Valerie Racine;
(2016)
Beyond Reductionism and Emergence: A Study of the Epistemic Practices in Gene Expression Research
(/isis/citation/CBB978842577/)
Article
Stotz, Karola;
(2004)
Introduction
(/isis/citation/CBB000600325/)
Article
Šustar, Predrag;
(2007)
Crick's Notion of Genetic Information and the “Central Dogma” of Molecular Biology
(/isis/citation/CBB000831432/)
Book
Giovanni Boniolo;
Marco J. Nathan;
(2016)
Philosophy of Molecular Medicine: Foundational Issues in Research and Practice
(/isis/citation/CBB433280242/)
Article
Taylor, Peter J.;
(2009)
Nothing Reliable about Genes or Environment: New Perspectives on Analysis of Similarity among Relatives in Light of the Possibility of Underlying Heterogeneity
(/isis/citation/CBB000954225/)
Book
Falk, Raphael;
(2009)
Genetic Analysis: A History of Genetic Thinking
(/isis/citation/CBB001250451/)
Book
Esha Shah;
(2018)
Who Is the Scientist-Subject?: Affective History of the Gene
(/isis/citation/CBB881962010/)
Article
Oliver M. Lean;
(2019)
Chemical arbitrariness and the causal role of molecular adapters
(/isis/citation/CBB162430966/)
Article
Morange, Michel;
(2006)
Les biologistes moléculaires face au problème de la vie
(/isis/citation/CBB000720177/)
Article
William R. Newman;
(2020)
Bad Chemistry: Basilisks and Women in Paracelsus and pseudo-Paracelsus
(/isis/citation/CBB593660659/)
Article
Hirai, Hiro;
(2007)
Interprétation chymique de la création et origine corpusculaire de la vie chez Athanasius Kircher
(/isis/citation/CBB000771334/)
Article
Kauffman, George B.;
(2006)
Heavy Hydrogen, Geophysics, and Planetary Science: A Retrospective View of Harold C. Urey (1893--1981) on the 75th Anniversary of His Discovery of Deuterium and the 25th Anniversary of His Death
(/isis/citation/CBB001252561/)
Chapter
Hirai, Hiro;
(2007)
Kircher's Chymical Interpretation of the Creation and Spontaneous Generation
(/isis/citation/CBB000773484/)
Book
Michael Fry;
(2016)
Landmark Experiments in Molecular Biology
(/isis/citation/CBB847837792/)
Article
Marcum, James A.;
(2002)
From Heresy to Dogma in Accounts of Opposition to Howard Temin's DNA Provirus Hypothesis
(/isis/citation/CBB000501150/)
Article
Winnie, John;
(2000)
Information and structure in molecular biology: Comments on Maynard Smith
(/isis/citation/CBB000110641/)
Book
Beckwith, Jonathan R.;
(2002)
Making Genes, Making Waves: A Social Activist in Science
(/isis/citation/CBB000301896/)
Article
Powell, Alexander;
O'Malley, Maureen A.;
Müller-Wille, Staffan;
Calvert, Jane;
Dupré, John;
(2007)
Disciplinary Baptisms: A Comparison of the Naming Stories of Genetics, Molecular Biology, Genomics and Systems Biology
(/isis/citation/CBB000831324/)
Article
Deichmann, Ute;
(2008)
Different Methods and Metaphysics in Early Molecular Genetics -- A Case of Disparity of Research?
(/isis/citation/CBB000931566/)
Be the first to comment!