Chapter ID: CBB639528782

Drug Discovery and Ayurveda (2015)

unapi

Since ancient times, drugs have been an essential part of the therapeutic and preventive armamentarium. Drugs can be natural products, synthetic chemicals, or biologicals. Advances in chemistry and biology have opened ways for powerful and specific drugs. However, today, new drug discovery is facing major challenges. Many drugs are failing due to toxicity and safety reasons. Currently, drug discovery is facing an innovation deficit. Ayurveda and Traditional and Complementary Medicine(T&CM) have described thousands of drugs and formulations. The authors explain the value of traditional knowledge, like Ayurveda, as a valuable resource for new drug discovery. A few case studies on drugs and adjuvants for metabolic and chronic diseases are presented to illustrate the potential of Ayurveda-inspired drug discovery. The issues related to quality control, standardization, and safety of botanical drugs, as well as the controversy surrounding mercury, and metal-based drugs will be discussed, with help of available scientific research. The authors suggest that the current one target–one drug discovery process needs to move toward formulation discovery, so that multiple targets are systematically addressed. The safe and rational combination of botanical drugs, psycho–neuro–immune–endocrinal and restorative regimens could be the key to future integrative medicine.

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Book Bhushan Patwardhan; Gururaj Mutalik MD; Girish Tillu (2015) Integrative Approaches for Health: Biomedical Research, Ayurveda and Yoga. unapi

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https://data.isiscb.org/isis/citation/CBB639528782/

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Authors & Contributors
Madhavan, Harilal
Mutalik, Gururaj
Tillu, Girish
Patwardhan, Bhushan
Y. Srinivasa Rao
Gaudillière, Jean-Paul
Journals
Asian Medicine: Tradition and Modernity
Studies in History of Medicine and Science
Social History
Osiris: A Research Journal Devoted to the History of Science and Its Cultural Influences
Journal of the History of Medicine and Allied Sciences
Isis: International Review Devoted to the History of Science and Its Cultural Influences
Publishers
University of Chicago Press
Routledge
New York University Press
Egbert Forsten
Diaphanes
Berghahn Books
Concepts
Medicine, traditional
Medicine, ayurvedic
Medicine
Traditional knowledge
India, civilization and culture
Medicine, herbal
People
Vagbhata
Galen
Time Periods
Modern
Ancient
19th century
Early modern
Medieval
20th century, early
Places
India
Kerala (India)
South Asia
Peru
Himalayan Mountains (Nepal)
South America
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