Morens, David M. (Author)
Folkers, Gregory K. (Author)
Fauci, Anthony S. (Author)
In the 17th and 18th centuries, the terms epidemic and pandemic were used vaguely and often interchangeably in various social and medical contexts. The first known use of the word pandemic, in 1666, referred to “a Pandemick, or Endemick, or rather a Vernacular Disease (a disease alwayes reigning in a Countrey)” [9, p. 3]. Two centuries later, in 1828, epidemiologist and lexicographer Noah Webster’s first edition of Webster’s Dictionary listed epidemic and pandemic as synonymous terms [10]. Webster, who had lived through the influenza pandemic of 1789–1790, which was the only major American influenza event of his adult lifetime, refers in his dictionary only to epidemic influenza and not to pandemic influenza [10]. Thus, by the early 19th century, the term epidemic, when used as a noun, had become the accepted term for what we would call today both an epidemic and a pandemic, with the term pandemic falling into increasing disuse
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