Article ID: CBB603005256

It Wasn't Supposed to Be a Coronavirus: The Quest for an Influenza A(h5n1)-Derived Vaccine and the Limits of Pandemic Preparedness (2020)

unapi

The COVID-19 pandemic has raised questions about what efforts were made across the world to prepare governments and healthcare systems for such an event. This spotlight article looks at developments made in “pre-pandemic preparedness planning” following a number of outbreaks of influenza type A virus in 1997. At that time, a specific avian influenza subtype, referred to as A(H5N1), wreaked havoc among fowl but also infected humans through direct transmission. The potential for slight genetic mutations that could make A(H5N1) more infectious, allowing human-to-human transmission, presented the threat of a deadly influenza pandemic. As a result, the U.S. government (and others coordinating through the World Health Organization) launched a pandemic preparation plan, including strategies to develop vaccines against A(H5N1) and its genetic lineages each year. This spotlight article discusses the events that led to the specific concern about A(H5N1) among public health officials, as well as early efforts to derive and stockpile an appropriate vaccine to protect against a possible pandemic. This perspective presents the challenges the world has faced, in recent history, in striving to keep one step ahead of pandemic threats.

...More
Citation URI
http://data.isiscb.org/isis/citation/CBB603005256/

Similar Citations

Article M. Kemal Temel; (2020)
The 1918 “Spanish Flu” Pandemic in the Ottoman Capital, Istanbul (/isis/citation/CBB539750154/) unapi

Book Carlo Caduff; (2015)
The Pandemic Perhaps: Dramatic Events in a Public Culture of Danger (/isis/citation/CBB736184954/) unapi

Article Michael P. Kelly; Federica Russo; (2021)
The epistemic values at the basis of epidemiology and public health (/isis/citation/CBB856188518/) unapi

Article Monica H. Green; (2020)
Emerging Diseases, Re-Emerging Histories (/isis/citation/CBB050271628/) unapi

Book Jacques Pépin; (2021)
The Origins of AIDS (/isis/citation/CBB084551418/) unapi

Article Wesley Shrum; John Aggrey; Andre Campos; Janaina Pamplona da Costa; Jan Joseph; Pablo Kreimer; Rhiannon Kroeger; Leandro Rodriguez Medina; Paige Miller; Antony Palackal; Ana Pandal de la Peza; Abou Traore; (October 2020)
Who’s afraid of Ebola? Epidemic fires and locative fears in the Information Age (/isis/citation/CBB307916719/) unapi

Article David S. Jones; (2020)
COVID-19, History, and Humility (/isis/citation/CBB009243530/) unapi

Article Jahn, Stefanie; (2014)
Die Grippe-Pandemie nach dem Ersten Weltkrieg und die Homöopathie im internationalen Vergleich (/isis/citation/CBB001421921/) unapi

Thesis Bresalier, M C; (cited 2010)
Transforming Flu: Medical Science and the Making of a Virus Disease in London, 1890--1939 (/isis/citation/CBB001567257/) unapi

Article Poliana Maia; Rosária Justi; Monique Santos; (2021)
Aspects About Science in the Context of Production and Communication of Knowledge of COVID-19 (/isis/citation/CBB033270554/) unapi

Article Nükhet Varlık; (2020)
Rethinking the History of Plague in the Time of Covid-19 (/isis/citation/CBB776966901/) unapi

Article Erica Charters; Richard A. McKay; (2020)
The History of Science and Medicine in the Context of COVID-19 (/isis/citation/CBB048196927/) unapi

Book Honigsbaum, Mark; (2014)
A History of the Great Influenza Pandemics: Death, Panic and Hysteria, 1830--1920 (/isis/citation/CBB001550988/) unapi

Book John Rhodes; (2021)
How to Make a Vaccine: An Essential Guide for COVID-19 and Beyond (/isis/citation/CBB659711878/) unapi

Article Geoffrey W. Rice; (2020)
How reminders of the 1918–19 pandemic helped Australia and New Zealand respond to COVID-19 (/isis/citation/CBB418629553/) unapi

Article Susanne Bauer; (2021)
Pandemic infrastructure: epidemiology as compartmentalization (/isis/citation/CBB933898213/) unapi

Article Anne-Emanuelle Birn; (2020)
How to Have Narrative-Flipping History in a Pandemic: Views of/from Latin America (/isis/citation/CBB573683614/) unapi

Authors & Contributors
Jahn, Stefanie
Honigsbaum, Mark
Bresalier, M C
Jones, David S.
Poliana Maia
Justi, Rosaria
Journals
Centaurus: International Magazine of the History of Mathematics, Science, and Technology
Mefisto: Rivista di medicina, filosofia, storia
Medizin, Gesellschaft, und Geschichte
Science and Education
Social Studies of Science
Journal of Global History
Publishers
I. B. Tauris
University of Cambridge (United Kingdom)
Cambridge University
Cambridge University Press
University of Chicago Press
University of California Press
Concepts
Public health
Pandemics
Medicine and society
Coronavirus disease 2019 (COVID-19)
Infectious diseases
Influenza
Places
London (England)
Democratic Republic of the Congo
Africa
New Zealand
Australia
Ottoman Empire
Times
21st century
20th century, early
20th century
19th century
Modern
Early modern
Comments

Be the first to comment!

{{ comment.created_by.username }} on {{ comment.created_on | date:'medium' }}

Log in or register to comment