The career of Melville Sahyun (1895-1977) comprised three major parts. In the first part he was engaged in diabetes research. In this period his most important contribution was the development of an industrial-scale process for the preparation of a purified insulin solution of standardized potency for clinical application that was based on his studies of insulin crystallization. He then turned to the biochemistry of amino acids and proteins. His major technical contribution in this area was the development of an amino acid supplement solution for intravenous or parenteral administration. In this period he also edited two important monographs on proteins and amino acids. The final phase of his career was devoted to drug discovery. The most noteworthy accomplishment in this period was the invention of the anti-inflammatory molecule tetrahydrozoline, which was formulated for ophthalmic use as Visine TM eye drops. (ResearchGate)
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