Book ID: CBB535457038

A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution (2017)


Doudna, Jennifer (Author)
Sternberg, Samuel H. (Author)

Houghton Mifflin Harcourt

Publication Date: 2017
Physical Details: 304
Language: English

A trailblazing biologist grapples with her role in the biggest scientific discovery of our era: a cheap, easy way of rewriting genetic code, with nearly limitless promise and peril. Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR—a revolutionary new technology that she helped create—to make heritable changes in human embryos. The cheapest, simplest, most effective way of manipulating DNA ever known, CRISPR may well give us the cure to HIV, genetic diseases, and some cancers, and will help address the world’s hunger crisis. Yet even the tiniest changes to DNA could have myriad, unforeseeable consequences—to say nothing of the ethical and societal repercussions of intentionally mutating embryos to create “better” humans.   Writing with fellow researcher Samuel Sternberg, Doudna shares the thrilling story of her discovery, and passionately argues that enormous responsibility comes with the ability to rewrite the code of life. With CRISPR, she shows, we have effectively taken control of evolution. What will we do with this unfathomable power?

Reviewed By

Review Stephan Guttinger (2018) Review of "A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution". Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences (pp. 32-35). unapi

Citation URI

Similar Citations

Book Walter Isaacson; (2021)
The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race (/isis/citation/CBB677514543/) unapi

Article Palladino, Paolo; (2003)
Life...On Biology, Biography, and Bio-power in the Age of Genetic Engineering (/isis/citation/CBB000500944/) unapi

Article Christian Ross; (2022)
Handservant of Technocracy: Public Engagement and Expertise in Heritable Human Genome Editing (/isis/citation/CBB828766557/) unapi

Article Andrew J. Hogan; (2016)
From Precaution to Peril: Public Relations Across Forty Years of Genetic Engineering (/isis/citation/CBB750225154/) unapi

Article Morgan Meyer; (2022)
Taking responsibility, making irresponsibility: Controversies in human gene editing (/isis/citation/CBB072011815/) unapi

Article Gomela, Elana; (2011)
Science (Fiction) and Posthuman Ethics: Redefining the Human (/isis/citation/CBB001212424/) unapi

Article Clayton, Jay; (2013)
The Ridicule of Time: Science Fiction, Bioethics, and the Posthuman (/isis/citation/CBB001200682/) unapi

Book Charles Lawson; Berris Charnley; (2015)
Intellectual Property and Genetically Modified Organisms: A Convergence in Laws (/isis/citation/CBB742382287/) unapi

Book Mark Coeckelbergh; (2013)
Human Being @ Risk: Enhancement, Technology, and the Evaluation of Vulnerability Transformations (/isis/citation/CBB944837263/) unapi

Article Cuevas-Badallo, Ana; Vermaas, Pieter E.; (2011)
A Functional ABC for Biotechnology and the Dissemination of Its Progeny (/isis/citation/CBB001024012/) unapi

Article Michel Morange; (2017)
Human Germline Editing: A Historical Perspective (/isis/citation/CBB176490993/) unapi

Article Dooren, Thom Van; (2007)
Terminated Seed: Death, Proprietary Kinship and the Production of (Bio)Wealth (/isis/citation/CBB000720317/) unapi

Book Bailey, Britt; Lappé, Marc; (2002)
Engineering the Farm: Ethical and Social Aspects of Agricultural Biotechnology (/isis/citation/CBB000201287/) unapi

Book Carlson, Robert H.; (2010)
Biology Is Technology: The Promise, Peril, and New Business of Engineering Life (/isis/citation/CBB001251428/) unapi

Article Sarah Babb; (2021)
The Privatization of Human Research Ethics: An American Story (/isis/citation/CBB733380502/) unapi

Book Holloway, Karla F. C.; (2011)
Private Bodies, Public Texts: Race, Gender, and a Cultural Bioethics (/isis/citation/CBB001200198/) unapi

Book Bernardino Fantini; Fabrizio Rufo; (2017)
Il codice della vita. Una storia della genetica tra scienza e bioetica (/isis/citation/CBB297801530/) unapi

Authors & Contributors
Bailey, Britt
Lappé, Frances Morre
Raffensperger, Carolyn
Lappé, Marc A.
Yi, Doogab
Thompson, Paul B.
European Journal for the History of Medicine and Health
Configurations: A Journal of Literature, Science, and Technology
Science as Culture
Journal of the History of Biology
Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences
American Literary History
Island Press
Duke University Press
Harvard University Press
University of Chicago Press
Simon & Schuster
Genetic engineering
Biology and ethics; bioethics
Science and ethics
Medicine and ethics
Berg, Paul
Doudna, Jennifer
Time Periods
21st century
20th century, late
20th century
19th century
United States
San Francisco, CA
West Germany
Stanford University
Human Genome Project

Be the first to comment!

{{ comment.created_by.username }} on {{ comment.created_on | date:'medium' }}

Log in or register to comment