Book ID: CBB535457038

A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution (2017)

unapi

Doudna, Jennifer (Author)
Sternberg, Samuel H. (Author)


Houghton Mifflin Harcourt


Publication Date: 2017
Physical Details: 304
Language: English

A trailblazing biologist grapples with her role in the biggest scientific discovery of our era: a cheap, easy way of rewriting genetic code, with nearly limitless promise and peril. Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR—a revolutionary new technology that she helped create—to make heritable changes in human embryos. The cheapest, simplest, most effective way of manipulating DNA ever known, CRISPR may well give us the cure to HIV, genetic diseases, and some cancers, and will help address the world’s hunger crisis. Yet even the tiniest changes to DNA could have myriad, unforeseeable consequences—to say nothing of the ethical and societal repercussions of intentionally mutating embryos to create “better” humans.   Writing with fellow researcher Samuel Sternberg, Doudna shares the thrilling story of her discovery, and passionately argues that enormous responsibility comes with the ability to rewrite the code of life. With CRISPR, she shows, we have effectively taken control of evolution. What will we do with this unfathomable power?

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Reviewed By

Review Stephan Guttinger (2018) Review of "A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution". Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences (pp. 32-35). unapi

Citation URI
https://data.isiscb.org/isis/citation/CBB535457038/

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Authors & Contributors
Yi, Doogab
Coeckelbergh, Mark
Isaacson, Walter
Amalia Leguizamón
Christian H. Ross
Lawson, Charles
Journals
Science as Culture
Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences
Spontaneous Generations
Social Studies of Science
Journal of the History of Biology
History and Philosophy of the Life Sciences
Publishers
University of Chicago Press
Springer
Simon & Schuster
Rowman & Littlefield
Routledge
Oxford University Press
Concepts
Genetic engineering
Biotechnology
CRISPR-Cas9
Biology and ethics; bioethics
Technoscience; science and technology studies
Agriculture
People
Doudna, Jennifer
Berg, Paul
Time Periods
21st century
20th century, late
20th century
Places
San Francisco (California)
Argentina
United States
Institutions
Stanford University
Science for the People (SftP)
Asilomar Conference on Recombinant DNA Molecules (1975)
Human Genome Project
Harvard University
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