Article ID: CBB447570859

The dextrorotatory sweet asparagine of Arnaldo Piutti: the original product is conserved in Florence (2018)

unapi

In 1886, Pasteur presented a note on the work of the Italian chemist Arnaldo Piutti concerning the difference between the two physical isomers (enantiomers) of asparagine. The octahedral crystal of asparagine appeared only as “levorotatory hemihedralism” but, in principle, should also exist as a dextrorotatory asparagine with a symmetric crystalline form. In 1886 Arnaldo Piutti isolated the dextrorotatory asparagines while he was working as an assistant of Ugo Schiff in Florence. He obtained also another unexpected information, of which only Pasteur immediately understood the importance: the dextrorotatory aspargine had a sweet taste. The dextrorotatory sweet asparagine of Arnaldo Piutti is conserved in the Schiff Collection of the Department of Chemistry “Ugo Schiff” at the University of Florence, and is the first compound where a relationship between the optical isomerism of a molecule and a different response of human receptors, in this case the taste, was observed.

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Authors & Contributors
Rasmussen, Seth C.
Aust, Rudolph
Bensaude-Vincent, Bernadette
Büttner, Johannes
Costa, Mariagrazia
Fontani, Marco
Journals
Bulletin for the History of Chemistry
Mitteilungen der Gesellschaft Deutscher Chemiker, Fachgruppe Geschichte der Chemie
Substantia: An International Journal of the History of Chemistry
Chirality: The Pharmacological, Biological, and Chemical Consequences of Molecular Asymmetry
East Asian Science, Technology, and Medicine
European Physical Journal H
Publishers
American Chemical Society
Ashgate, Variorum
Firenze University Press
HYLE Publications
Mimesis
The MIT Press
Concepts
Chemistry
Organic chemistry
Chemical synthesis
Chemical elements
Biochemistry
Plastics; rubber; polymers
People
Pasteur, Louis
Wöhler, Friedrich
Berthelot, Marcelin Pierre Eugène
Berzelius, Jons Jakob
Curie, Pierre
Davy, Humphry
Time Periods
20th century
19th century
21st century
18th century
Places
Germany
China
France
Italy
Russia
United States
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