Article ID: CBB434545406

The Molecular Basis of Evolution and Disease: A Cold War Alliance (2019)

unapi

This paper extends previous arguments against the assumption that the study of variation at the molecular level was instigated with a view to solving an internal conflict between the balance and classical schools of population genetics. It does so by focusing on the intersection of basic research in protein chemistry and the molecular approach to disease with the enactment of global health campaigns during the Cold War period. The paper connects advances in research on protein structure and function as reflected in Christian Anfinsen’s The molecular basis of evolution, with a political reading of Emilé Zuckerkandl and Linus Pauling’s identification of molecular disease and evolution. Beyond atomic fallout, these advances constituted a rationale for the promotion of genetic surveys of human populations in the Third World, in connection with international health programs. Light is shed not only on the experimental roots of the molecular challenge but on the broader geopolitical context where the rising role of biomedicine and public health (particularly the malaria eradication campaigns) had an impact on evolutionary biology.

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Article Edna Suárez-Díaz (2019) Erratum to: The Molecular Basis of Evolution and Disease: A Cold War Alliance. Journal of the History of Biology (pp. 347-347). unapi

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Article Edna Suárez-Díaz (2019) Erratum to: The Molecular Basis of Evolution and Disease: A Cold War Alliance. Journal of the History of Biology (pp. 347-347). unapi

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Authors & Contributors
Montmerle, Thierry
Rispoli, Giulia
Lidiane Soares Rodrigues
Yi Zhou
Drachman, Daniel B.
Olšáková, Doubravka
Journals
Historical Studies in the Natural Sciences
Social Studies of Science
Science in Context
Perspectives in Biology and Medicine
Minerva: A Review of Science, Learning and Policy
Mendel Newsletter
Publishers
Johns Hopkins University Press
University of Exeter (United Kingdom)
University of Texas at Austin
Springer
Cornell University Press
University of Kansas
Concepts
Molecular biology
Disease and diseases
Geopolitics
Evolution
Cold War
Science and politics
People
Pauling, Linus Carl
Zuckerkandl, Emile
McNamara, Robert Strange
Richardson, Jane
Kistiakowsky, George Bogdan
Hodgkin, Dorothy Crowfoot
Time Periods
20th century, late
21st century
20th century
20th century, early
19th century
Places
China
Uganda
United States
Taiwan
Soviet Union
India
Institutions
Johns Hopkins University
Boston City Hospital
International Council of Scientific Unions
Campaign for Nuclear Disarmament
World Bank
Ford Foundation
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