Article ID: CBB416070087

Rethinking health and disease in the era of personalized medicine (2021)


Genome-based medicine, usually referred to as personalized medicine, aims to provide tailored treatments for a single patient according to his/her genome. Thanks to correlations between genotype and phenotype, it is also able to assess the chances of developing a disease given to the presence of a specific genetic mutation. Within the aforementioned paradigm, the first challenge to address is to properly define what is usually meant by the expression ‘personalized medicine’, specifying the methodologies it uses and the premises it is based on. Then it appears fundamental to discuss whether and how such vision entails any change for our theoretical concepts of health and disease. I will argue that this is the case and, in particular, that being able to predict the probability of diseases’ occurrence can significantly affect our philosophical concepts of disease, illness, and sickness in different ways.

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Authors & Contributors
Lee, Sandra Soo-Jin
Bliss, Catherine Anne
Lock, Margaret M.
Hout, Sanne van der
Frank, Reanne
Huneman, Philippe
Mefisto: Rivista di medicina, filosofia, storia
Social Studies of Science
Science, Technology and Human Values
Medicina nei Secoli - Arte e Scienza
History and Philosophy of the Life Sciences
Annals of the American Academy of Political and Social Science
Stanford University Press
Cornell University
Profile Books
Rutgers University Press
Human genetics
Disease and diseases
Starobinski, Jean
Time Periods
21st century
20th century
20th century, late
19th century
United States
Great Britain
South Africa
Human Genome Project

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