Article ID: CBB399574473

Dogs for Life: Beagles, Drugs, and Capital in the Twentieth Century (2022)

unapi

This article tracks the transformation of beagle dogs from a common breed in mid-twentieth century American laboratories to the de jure standard in global toxicological research by the turn of the twenty-first. The breed was dispersed widely due to the expanding use of dogs in pharmacology in the 1950s and a worldwide crisis around pharmaceutical safety following the thalidomide scandal of the 1960s. Nevertheless, debates continued for decades over the beagle’s value as a model of carcinogenicity, even as the dogs became legislated stand-ins for human beings in multiple countries. Situating beagles as a biocommodity, the article calls for more sustained attention to the “political economy” of laboratory organism breeding, use, and production. The story of American commercial breeder Marshall Farms offers insight into the role of for-profit companies in contemporary laboratory animal provision, as the article makes a case for the value of a global perspective on transnational corporations as key sites of scientific practice and collaboration.

...More
Included in

Article Brad Bolman (2022) Introduction: What Right? Which Organisms? Why Jobs?. Journal of the History of Biology (pp. 3-13). unapi

Citation URI
https://data.isiscb.org/isis/citation/CBB399574473/

Similar Citations

Article Hannah Landecker; (2016)
It is what it eats: Chemically defined media and the history of surrounds (/isis/citation/CBB598422047/)

Article Robert G. W. Kirk; Edmund Ramsden; (2021)
"Havens of mercy”: health, medical research, and the governance of the movement of dogs in twentieth-century America (/isis/citation/CBB713465624/)

Article Pemberton, Neil; (2013)
The Bloodhound's Nose Knows? Dogs and Detection in Anglo-American Culture (/isis/citation/CBB001213635/)

Article Simon Lohse; (2021)
Scientific inertia in animal-based research in biomedicine (/isis/citation/CBB124857110/)

Article Rebecca A. Hardesty; (2018)
Much ado about mice: Standard-setting in model organism research (/isis/citation/CBB487976291/)

Article Robert Kohler; (2022)
Lords of the Fly Revisited (/isis/citation/CBB701830584/)

Article Brad Bolman; (2021)
Pig Mentations: Race and Face in Radiobiology (/isis/citation/CBB398870305/)

Book Stephanie Elizabeth Mohr; (2018)
First in Fly: Drosophila Research and Biological Discovery (/isis/citation/CBB668155327/)

Chapter Rheinberger, Hans-Jörg; (2010)
The Art of Exploring the Unknown: Views on Contemporary Research in the Life Sciences (/isis/citation/CBB001023236/)

Article Angela N. H. Creager; (2022)
Model Organisms Unbound (/isis/citation/CBB532396920/)

Article Herran, Néstor; (2009)
Isotope Networks: Training, Sales and Publications, 1946--1965 (/isis/citation/CBB000931753/)

Article Brad Bolman; (2022)
Introduction: What Right? Which Organisms? Why Jobs? (/isis/citation/CBB702630053/)

Article Per-Anders Svärd; Helena Tinnerholm Ljungberg; (2021)
Fetal and animal research in Sweden: The construction of viable lives in regulatory policy debates, 1970–1980 (/isis/citation/CBB965696186/)

Authors & Contributors
Brad Bolman
Tara Suri
Kirk, Robert G. W.
Karl Bruno
Tinnerholm Ljungberg, Helena
Holmes, Tarquin
Concepts
Experimental organisms
Laboratory techniques and procedures
Laboratory animals
Animal experimentation
Models and modeling in science
Standards and standardization
Time Periods
20th century
21st century
20th century, late
19th century
Places
United States
Europe
Sweden
United Kingdom
Washington (state, U.S.)
Americas
Institutions
Hanford Nuclear Site (Washington)
Harvard University
Comments

Be the first to comment!

{{ comment.created_by.username }} on {{ comment.created_on | date:'medium' }}

Log in or register to comment