Article ID: CBB399574473

Dogs for Life: Beagles, Drugs, and Capital in the Twentieth Century (2022)


This article tracks the transformation of beagle dogs from a common breed in mid-twentieth century American laboratories to the de jure standard in global toxicological research by the turn of the twenty-first. The breed was dispersed widely due to the expanding use of dogs in pharmacology in the 1950s and a worldwide crisis around pharmaceutical safety following the thalidomide scandal of the 1960s. Nevertheless, debates continued for decades over the beagle’s value as a model of carcinogenicity, even as the dogs became legislated stand-ins for human beings in multiple countries. Situating beagles as a biocommodity, the article calls for more sustained attention to the “political economy” of laboratory organism breeding, use, and production. The story of American commercial breeder Marshall Farms offers insight into the role of for-profit companies in contemporary laboratory animal provision, as the article makes a case for the value of a global perspective on transnational corporations as key sites of scientific practice and collaboration.

Included in

Article Brad Bolman (2022) Introduction: What Right? Which Organisms? Why Jobs?. Journal of the History of Biology (pp. 3-13). unapi

Citation URI

Similar Citations

Article Hannah Landecker; (2016)
It is what it eats: Chemically defined media and the history of surrounds (/isis/citation/CBB598422047/) unapi

Article Pemberton, Neil; (2013)
The Bloodhound's Nose Knows? Dogs and Detection in Anglo-American Culture (/isis/citation/CBB001213635/) unapi

Article Rebecca A. Hardesty; (2018)
Much ado about mice: Standard-setting in model organism research (/isis/citation/CBB487976291/) unapi

Article Simon Lohse; (2021)
Scientific inertia in animal-based research in biomedicine (/isis/citation/CBB124857110/) unapi

Article Robert Kohler; (2022)
Lords of the Fly Revisited (/isis/citation/CBB701830584/) unapi

Article Brad Bolman; (2021)
Pig Mentations: Race and Face in Radiobiology (/isis/citation/CBB398870305/) unapi

Chapter Rheinberger, Hans-Jörg; (2010)
The Art of Exploring the Unknown: Views on Contemporary Research in the Life Sciences (/isis/citation/CBB001023236/) unapi

Book Stephanie Elizabeth Mohr; (2018)
First in Fly: Drosophila Research and Biological Discovery (/isis/citation/CBB668155327/) unapi

Article Angela N. H. Creager; (2022)
Model Organisms Unbound (/isis/citation/CBB532396920/) unapi

Article Herran, Néstor; (2009)
Isotope Networks: Training, Sales and Publications, 1946--1965 (/isis/citation/CBB000931753/) unapi

Article Brad Bolman; (2022)
Introduction: What Right? Which Organisms? Why Jobs? (/isis/citation/CBB702630053/) unapi

Article Per-Anders Svärd; Helena Tinnerholm Ljungberg; (2021)
Fetal and animal research in Sweden: The construction of viable lives in regulatory policy debates, 1970–1980 (/isis/citation/CBB965696186/) unapi

Article Morgan, Gregory J.; (2014)
Ludwik Gross, Sarah Stewart, and the 1950s Discoveries of Gross Murine Leukemia Virus and Polyoma Virus (/isis/citation/CBB001421646/) unapi

Article Nicole Welk-Joerger; (2022)
The Business with “Bugs”: Ruminology and the Commercial Feed Industry in the United States (/isis/citation/CBB620126843/) unapi

Authors & Contributors
Brad Bolman
Herran, Néstor
Smocovitis, Vassiliki Betty
Rheinberger, Hans-Jörg
Pemberton, Neil
Kirk, Robert
Journal of the History of Biology
Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences
Studies in History and Philosophy of Science
Dynamis: Acta Hispanica ad Medicinae Scientiarumque Historiam Illustrandam
Historical Studies in the Natural Sciences
Endeavour: Review of the Progress of Science
Harvard University Press
Experimental organisms
Laboratory techniques and procedures
Laboratory animals
Animal experimentation
Standardization and standards
Babcock, E. B. (Ernest Brown)
Stewart, Sarah
Gross, Ludwik
Bustad, Leo K.
Time Periods
20th century
21st century
20th century, late
19th century
United States
Great Britain
United Kingdom
Washington (state, U.S.)
University of California, Berkeley
Hanford Nuclear Site (Washington)

Be the first to comment!

{{ comment.created_by.username }} on {{ comment.created_on | date:'medium' }}

Log in or register to comment