Article ID: CBB369219796

Locating the ‘culture wars’ in laboratory animal research: National constitutions and global competition (2021)

unapi

The increasingly global scope of biomedical research and testing using animals is generating disagreement over the best way to regulate laboratory animal science and care. Despite many common aims, the practices through which political and epistemic authority are allocated in the regulations around animal research varies internationally, coming together in what can be identified as different national constitutions. Tensions between these periodically erupt within the laboratory animal research community as a ‘cultural war’ between those favouring centralised control and those advocating local flexibility. Drawing on long-term engagement with key events and actors in these policy debates, I propose these national differences in the constitution of animal research can be understood through the intersection of two key variables: i) the location of institutional responsibility to permit research projects and ii) the distribution of epistemic authority to shape research practices. These variables are used to explain the development of different policy frameworks in the UK, Europe, and the USA, and identify where there is convergence and divergence in practice. Concluding, I suggest the way these approaches are combined and enacted in different countries reflects different national civic epistemologies, which are coming into conflict in the increasingly global networks of laboratory animal science.

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Authors & Contributors
Brad Bolman
Colleen Lanier-Christensen
Abboud, Alexis J.
Hauskeller, Christine
Kirk, Robert G. W.
Rachel K. Gibson
Journals
Journal of the History of Biology
Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences
Science, Technology and Human Values
Studies in History and Philosophy of Science
Science as Culture
Isis: International Review Devoted to the History of Science and Its Cultural Influences
Publishers
Arizona State University
Oxford University Press
Concepts
Experimental organisms
Laboratory animals
Regulation
Laboratory techniques and procedures
Models and modeling in science
Biology
People
Bustad, Leo K.
Weismann, August
Rader, Karen A.
Morgan, Thomas Hunt
Michurin, Ivan Vladimirovich
Lysenko, Trofim Denisovich
Time Periods
21st century
20th century
20th century, late
20th century, early
19th century
Places
United States
Europe
United Kingdom
Moscow (Russia)
Washington (state, U.S.)
Sweden
Institutions
Organisation for Economic Co-operation and Development
Diagnostic and Statistical Manual of Mental Disorders (DSM)
Hanford Nuclear Site (Washington)
World Health Organization (WHO)
National Health Service (Great Britain)
American Psychiatric Association
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