Article ID: CBB362815001

Changing Infrastructural Practices: Routine and Reproducibility in Automated Interdisciplinary Bioscience (2020)

unapi

Proponents of engineering and design approaches to biology aim to make interdisciplinary bioscience research faster and more reproducible. This paper outlines and deploys a practice-based approach to analyses of infrastructure that focuses on the routine epistemic activities and charts how two such routines are unsettled and resettled in the background of epistemic culture. This paper describes attempts to bring about new research infrastructures in synthetic biology using robotics and software-enabled design. A focus on the skills of pipetting shows how established manual labor has to be reconfigured to fit with novel robotic automations. An analysis of curating frozen materials shows that automated design presents new problems for the established activities of storing and retrieving biological materials. These movements, while transient, have implications for organizing interdisciplinary collaboration, research productivity, and enabling greater reproducibility. This paper explores the idea of infrastructure as practice and shows how this has important implications for studies of research infrastructures. This article discusses the main contributions of this approach for analysts of infrastructure in terms of movements, temporalities, and ethics and offers suggestions for what the research implies for synthetic biology.

...More
Citation URI
https://data.isiscb.org/isis/citation/CBB362815001/

Similar Citations

Article Deichmann, Ute; (2009)
Chemistry and the Engineering of Life around 1900: Research and Reflections by Jacques Loeb (/isis/citation/CBB001230120/)

Article Mike Ananny; (January 2016)
Toward an Ethics of Algorithms: Convening, Observation, Probability, and Timeliness (/isis/citation/CBB726764977/)

Thesis Kendall Milar Thompson; (2015)
I, Robot: Nikola Tesla's Telautomaton (/isis/citation/CBB148337672/)

Book Sophia Roosth; (2017)
Synthetic: How Life Got Made (/isis/citation/CBB671229087/)

Article Talia Dan-Cohen; (September 2016)
Ignoring Complexity: Epistemic Wagers and Knowledge Practices among Synthetic Biologists (/isis/citation/CBB599343715/)

Article Nerem, Robert; (Winter 1997)
The Emergence of Bioengineering (/isis/citation/CBB467297363/)

Article Bueno, Otávio; (2011)
When Physics and Biology Meet: The Nanoscale Case (/isis/citation/CBB001024003/)

Article Peretó, J.; Catalá-Gorgues, J. I.; (2007)
The Renaissance of Synthetic Biology (/isis/citation/CBB001023444/)

Book Michel Morange; (2020)
The Black Box of Biology: A History of the Molecular Revolution (/isis/citation/CBB035364586/)

Book Susan Merrill Squier; (2017)
Epigenetic Landscapes: Drawings as Metaphor (/isis/citation/CBB524640115/)

Chapter Bensaude-Vincent, Bernadette; (2007)
Nanobots and Nanotubes: Two Alternative Biomimetic Paradigms of Nanotechnology (/isis/citation/CBB000774731/)

Book Negrotti, Massimo; (2012)
The Reality of the Artificial: Nature, Technology and Naturoids (/isis/citation/CBB001213202/)

Article Vermeulen, Niki; Parker, John N.; Penders, Bart; (2013)
Understanding Life Together: A Brief History of Collaboration in Biology (/isis/citation/CBB001213643/)

Article Noguera-Solano, Ricardo; Ruiz-Gutierrez, Rosaura; Rodriguez-Caso, Juan Manuel; (2013)
Genome: Twisting Stories with DNA (/isis/citation/CBB001213636/)

Book Christopher D. Lynn; Amanda L. Glaze; William A. Evans; Laura K. Reed; (2017)
Evolution Education in the American South: Culture, Politics, and Resources in and around Alabama (/isis/citation/CBB785010111/)

Article Nadine Levin; Sabine Leonelli; Dagmara Weckowska; David Castle; John Dupré; (2016)
How Do Scientists Define Openness? Exploring the Relationship Between Open Science Policies and Research Practice (/isis/citation/CBB530775467/)

Article Jane Calvery; Pablo Schyfter; (April 2017)
What can science and technology studies learn from art and design? Reflections on ‘Synthetic Aesthetics’ (/isis/citation/CBB521887641/)

Article Massimiliano Simons; (2021)
Synthetic biology as a technoscience: The case of minimal genomes and essential genes (/isis/citation/CBB407365411/)

Authors & Contributors
Lynn, Christopher D.
Weckowska, Dagmara
Marco Deseriis
Simons, Massimiliano
Ananny, Mike
Nerem, Robert
Journals
Science, Technology, and Human Values
Endeavour: Review of the Progress of Science
Biological Theory
Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences
Studies in History and Philosophy of Science
Social Studies of Science
Publishers
University of Chicago Press
University of California, Los Angeles
Springer
Palgrave Macmillan
Harvard University Press
Duke University Press
Concepts
Biology
Synthetic biology; bioengineering
Research
Design
Genetics
Life sciences
People
Koonin, Eugene V.
Waddington, Conrad Hal
Winkler, Hans Karl Albert
Venter, J. Craig
Tesla, Nikola
Morowitz, Harold J.
Time Periods
21st century
20th century, late
20th century
19th century
Modern
Places
Southern states (U.S.)
Austria
Alabama (U.S.)
Great Britain
Institutions
Census of Marine Life (1999-2009)
Human Genome Project
Comments

Be the first to comment!

{{ comment.created_by.username }} on {{ comment.created_on | date:'medium' }}

Log in or register to comment