Article ID: CBB360249828

Vincenzo Tiberio: la prima antibiotico-terapia sperimentale in vivo (2017)

unapi

This paper describes the first in vivo experimental antibiotic therapy in the history of Medicine. In 1895, in Arzano (Naples, Italy), the physician and scientist Vincenzo Tiberio discovered the bactericidal power of the molds. Tiberio analyzed three molds (Aspergillus flavescens, Penicillium glaucum, Mucor mucedo) in the laboratory, first in vitro and then in vivo on mice and rabbits. He carried out the whole experimental cycle: from the discovery to the observation of the phenomenon, to the analysis in the laboratory, and to the production of the medicine. Vincenzo Tiberio discovered the penicillin almost thirty years earlier than Alexander Fleming. What he lacked was the mass production and industrialization of the drug. Why? Fault of the society? Economic and cultural backwardness of Italy? Probably the international scientific community was not ready for such a revolutionary discovery, that would have saved millions of lives.

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https://data.isiscb.org/isis/citation/CBB360249828/

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Authors & Contributors
Neumeyer, Sybille
Weed, Kym
Garbarino, Maria Carla
D'Abramo, Flavio
Kuznetsov, Vyacheslav A.
Worboys, Michael
Concepts
Bacteriology
Medicine
Microbiology
Antibiotics
Public health
Infectious diseases
Time Periods
19th century
20th century, early
20th century
20th century, late
Places
United States
Italy
Philadelphia, PA
Milan (Italy)
Glasgow (Scotland)
Ukraine
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