Article
ID: CBB360249828

Vincenzo Tiberio: la prima antibiotico-terapia sperimentale in vivo (2017)

unapi
Medicine Microbiology Antibiotics Bacteriology 19th century 20th century, early Italy Tiberio, Vincenzo

This paper describes the first in vivo experimental antibiotic therapy in the history of Medicine. In 1895, in Arzano (Naples, Italy), the physician and scientist Vincenzo Tiberio discovered the bactericidal power of the molds. Tiberio analyzed three molds (Aspergillus flavescens, Penicillium glaucum, Mucor mucedo) in the laboratory, first in vitro and then in vivo on mice and rabbits. He carried out the whole experimental cycle: from the discovery to the observation of the phenomenon, to the analysis in the laboratory, and to the production of the medicine. Vincenzo Tiberio discovered the penicillin almost thirty years earlier than Alexander Fleming. What he lacked was the mass production and industrialization of the drug. Why? Fault of the society? Economic and cultural backwardness of Italy? Probably the international scientific community was not ready for such a revolutionary discovery, that would have saved millions of lives.

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Authors & Contributors
Neumeyer, Sybille
Weed, Kym
Garbarino, Maria Carla
D'Abramo, Flavio
Kuznetsov, Vyacheslav A.
Worboys, Michael
Journals
Journal of Medical Biography
Social History of Medicine
Medicina nei Secoli - Arte e Scienza
Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences
Science in Context
Journal of the History of Medicine and Allied Sciences
Publishers
University of North Carolina at Chapel Hill
Oxford University Press
Boston Medical Library in the Francis A. Countway Library of Medicine
Concepts
Bacteriology
Medicine
Microbiology
Antibiotics
Public health
Anthrax
People
Bardakh, Yakov Yulievich (1857–1929)
Koch, Robert
Smith, Theobald
Plaut, Hugo Carl
Pasteur, Louis
Negri, Adelchi
Time Periods
19th century
20th century, early
20th century
20th century, late
Places
United States
Italy
France
Philadelphia, PA
Milan (Italy)
Glasgow (Scotland)
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