Thesis ID: CBB313774069

A Biography of Endocrine Disruptors: The Narrative Surrounding the Appearance and Regulation of a New Category of Toxic Substances (2018)

unapi

Endocrine disruptors are chemicals that interact with the hormone system to negative effect. They ‘disrupt’ normal processes to cause diseases like vaginal cancer and obesity, reproductive issues like t-shaped uteri and infertility, and developmental abnormalities like spina bifida and cleft palate. These chemicals are ubiquitous in our daily lives, components in everything from toothpaste to microwave popcorn to plastic water bottles. My dissertation looks at the history, science, and regulation of these impactful substances in order to answer the question of how endocrine disruptors appeared, got interpreted by different groups, and what role science played in the process. My analysis reveals that endocrine disruptors followed a unique science policy trajectory in the US, rapidly going from their proposal in 1991 to their federal regulation in 1996, even amid intense and majority scientific disagreement over whether the substances existed at all. That trajectory resulted from the work of a small number of scientist-activists who constructed a concept and category as scientific, social, and regulatory. By playing actors from each sphere against each other and advancing a very specific scientific narrative that fit into a regulatory and social window of opportunity in the 1990s, those scientist-activists made endocrine disruptors a national issue that few could ignore. Those actions resulted in the Endocrine Disruptor Screening Program, a heavily-criticized and ineffective regulatory program. My dissertation tells a story of the past that informs the present. In 2018, the work of researchers, public media, and policymakers in the 1990s continues to play out, evident in the deep scientific division over endocrine disrupting effects and the inability of the European Union to settle on even a definition of endocrine disruptors for regulation purposes.

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Citation URI
https://data.isiscb.org/isis/citation/CBB313774069/

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Authors & Contributors
Aldrich, Mark
Bonnichon, Philippe
Charbit, Lionel
Knegtmans, Peter Jan
Krementsov, Nikolai L.
Krige, John G.
Journals
Social Studies of Science
American Heritage of Invention and Technology
American Historical Review
Environmental History
Histoire des Sciences Médicales
Isis: International Review Devoted to the History of Science and Its Cultural Influences
Publishers
University of Chicago Press
Boom
Chronos
Johns Hopkins University Press
Science History Publications
W. W. Norton & Co.
Concepts
Regulation
Hormones
Endocrinology
Medicine
Physiology
Pharmacy
People
Atherton, Gertrude Franklin Horn
Brinkley, John Richard
Higby, Gregory J.
Westman, Axel
Ernst Laqueur
Myerson, Abraham
Time Periods
21st century
20th century, late
20th century, early
20th century
19th century
Places
United States
Europe
Soviet Union
California (U.S.)
Switzerland
Netherlands
Institutions
United States. Environmental Protection Agency
United States Federal Communications Commission
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