Article ID: CBB289456943

Die Neutronentherapie: Ein Experimentalsystem der Radioonkologie (2017)

unapi

Neutron Therapy: An Experimental System in Radiooncology. The history of the use of neutrons in radiotherapy will be revisited by focusing on the ideas, theories and experiments that led to first clinical studies. For addressing epistemological questions regarding biological effects of fast neutrons, the notion of an “experimental system” is employed and its evolution over time discussed. Taking up the analytical framework of Hans-Jörg Rheinberger, biological effects and the physical instrument “cyclotron” are conceptualized in terms of epistemic and technical objects. It is shown that the epistemic object “biological effects of neutrons” could never reach the status of a technical object and – more strikingly – that the cyclotron itself returned to being an epistemic object in the context of medicine. So there is a misunderstanding of the different roles epistemic and technical objects have to play in the framework of an experimental system. This misunderstanding led to today's highly controversial discussions about the application of neutrons in radiotherapy.

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Authors & Contributors
Crease, Robert P.
Adamson, Matthew
Bai, Xin
Dehue, Trudy
Doing, Park A.
Giudice, Gian Francesco
Journals
Physics in Perspective
Historical Studies in the Physical and Biological Sciences
History of the Human Sciences
Chinese Journal for the History of Science and Technology
Dynamis: Acta Hispanica ad Medicinae Scientiarumque Historiam Illustrandam
European Physical Journal H
Publishers
Johns Hopkins University Press
MIT Press
World Scientific
Concepts
Particle accelerators
Scientific apparatus and instruments
Physics
Atomic, nuclear, and particle physics
Experiments and experimentation
Big science
People
Fritsch, Gustav
Hitzig, Eduard
Joliot-Curie, Frédéric
Time Periods
20th century, late
21st century
20th century
20th century, early
19th century
Places
France
United States
Germany
Switzerland
Belgium
China
Institutions
Brookhaven National Laboratory (United States)
Large Hadron Collider (LHC)
Collège de France, Paris
Cornell University
European Organization for Nuclear Research (CERN)
France. Commissariat à l'Energie Atomique
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