Book ID: CBB126606472

Sheila: Unlocking the Treatment for PKU (2020)

unapi

In 1951 a two year old infant Sheila Jones was diagnosed at Birmingham Children's Hospital (BCH) with a rare condition Phenylketonuria (PKU). There was no treatment but, not accepting this, her distraught mother Mary persevered until she found help from three pioneering doctors at BCH: Dr Horst Bickel, Dr John Gerrard and Dr Evelyn Hickmans. In the hospital laboratory they worked tirelessly to prepare a special formula and Sheila was the first person in the world to receive dietary treatment for PKU. Until now, little has been known about the life of Sheila, and her family in Birmingham, and the hardships and sacrifices they endured. It is a remarkable story of a brave little girl, her brothers, and her courageous and tenacious mother. Sheila's contribution is immense; it led to the introduction of newborn screening and worldwide treatment for PKU. It is a great sadness that Sheila herself was unable to benefit long term but her legacy is a triumph for all those with PKU. This is Sheila's story until her death in Birmingham in 1999 and will be important to people with PKU, their families, health professionals and readers interested in the history of medicine.

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Reviewed By

Review Douglas J. Lanska (2021) Review of "Sheila: Unlocking the Treatment for PKU". Journal of the History of the Neurosciences (pp. 332-334). unapi

Citation URI
https://data.isiscb.org/isis/citation/CBB126606472/

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Authors & Contributors
Wolf, Jacqueline H.
Barakat, Meredith
Bastian, John F.
Berney, Adrienne W.
Boon, Heather
Brosco, Jeffrey P.
Journals
Bulletin of the History of Medicine
History of Psychiatry
History of the Human Sciences
Journal of the History of Medicine and Allied Sciences
Llull: Revista de la Sociedad Española de Historia de las Ciencias y de las Técnicas
Medical History
Publishers
University of Pennsylvania
Harvard University Press
Johns Hopkins University Press
UCL Press
University of Michigan Press
Northwestern University
Concepts
Pediatrics
Medicine
Children's diseases
Nutrition; dietetics
Public health
Epidemiology
People
Janeway, Charles A.
Time Periods
20th century
20th century, late
19th century
17th century
21st century
Places
Great Britain
British Isles
United States
Canada
Europe
Germany
Institutions
General Medical Council (Great Britain)
National Health Service (Great Britain)
Harvard University
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