Article ID: CBB072011815

Taking responsibility, making irresponsibility: Controversies in human gene editing (2022)

unapi

In current discussions, human germline editing is often called ‘irresponsible’. Looking at the international summits on human gene editing held in 2015 and in 2018 and the announcement by He Jiankui of the birth of two gene-edited babies in November 2018, this article analyses how ‘irresponsible’ research was the result of various (dis)qualifications and demarcations. Against a background of discussions of responsibility, an individual scientist was singled out, his experiments were scrutinized for their soundness, legality and safety and ethical and moral stances were questioned. These are features of a process that I call ‘irresponsibilization’. This irresponsibilization of research is entangled with calls for further action: Irresponsible research like that of He Jiankui should be contained, the veracity of knowledge claims needs to be confirmed, and institutions and decision-makers are called to act. The controversy turned ‘irresponsible’ into an active category, and rendered explicit its political, institutional and practical ramifications.

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Authors & Contributors
Benedict Douglas
Trainque, Jarrod
Otsuka, Yoshiki
Jacobson, Arne
Isaacson, Walter
Larry Au
Journals
East Asian Science, Technology and Society: An International Journal
Science as Culture
Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences
Spontaneous Generations
Social Studies of Science
Science, Technology and Human Values
Publishers
Simon & Schuster
Rowman & Littlefield
Routledge
Oxford University Press
Houghton Mifflin Harcourt
Harvard University
Concepts
Genetic engineering
Technoscience; science and technology studies
CRISPR-Cas9
Biomedicine
Research
Biotechnology
People
Doudna, Jennifer
He, Jiankui
Time Periods
21st century
20th century, late
Places
South Korea
Singapore
United States
Japan
Europe
China
Institutions
Science for the People (SftP)
Asilomar Conference on Recombinant DNA Molecules (1975)
National Institute of Health (U.S.)
Harvard University
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