Book ID: CBB035364586

The Black Box of Biology: A History of the Molecular Revolution (2020)

unapi

Morange, Michel (Author)
Cobb, Matthew (Translator)


Cobb, Matthew
Harvard University Press


Publication Date: 2020
Physical Details: 528
Language: English

In this masterful account, a historian of science surveys the molecular biology revolution, its origin and continuing impact.Since the 1930s, a molecular vision has been transforming biology. Michel Morange provides an incisive and overarching history of this transformation, from the early attempts to explain organisms by the structure of their chemical components, to the birth and consolidation of genetics, to the latest technologies and discoveries enabled by the new science of life. Morange revisits A History of Molecular Biology and offers new insights from the past twenty years into his analysis.The Black Box of Biology shows that what led to the incredible transformation of biology was not a simple accumulation of new results, but the molecularization of a large part of biology. In fact, Morange argues, the greatest biological achievements of the past few decades should still be understood within the molecular paradigm. What has happened is not the displacement of molecular biology by other techniques and avenues of research, but rather the fusion of molecular principles and concepts with those of other disciplines, including genetics, physics, structural chemistry, and computational biology. This has produced decisive changes, including the discoveries of regulatory RNAs, the development of massive scientific programs such as human genome sequencing, and the emergence of synthetic biology, systems biology, and epigenetics.Original, persuasive, and breathtaking in its scope, The Black Box of Biology sets a new standard for the history of the ongoing molecular revolution.

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Reviewed By

Review Jean-Baptiste Grodwohl (2023) Review of "The Black Box of Biology: A History of the Molecular Revolution". British Journal for the History of Science (pp. 588-589). unapi

Essay Review Daniele Cozzoli (2022) The Age of Molecular Biology. Centaurus: International Magazine of the History of Mathematics, Science, and Technology (pp. 947-952). unapi

Review Kostas Kampourakis (2022) Review of "The Black Box of Biology: A History of the Molecular Revolution". History and Philosophy of the Life Sciences (p. 5). unapi

Review Koen B. Tanghe (2020) Review of "The Black Box of Biology: A History of the Molecular Revolution". Journal of the History of Biology (pp. 489-492). unapi

Citation URI
https://data.isiscb.org/isis/citation/CBB035364586/

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Authors & Contributors
Stevens, Hallam
Bueno, Otávio
Calvert, Jane
Deichmann, Ute
Fantini, Bernardino
Gross, Fridolin
Journals
Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences
History and Philosophy of the Life Sciences
Biological Theory
Endeavour: Review of the Progress of Science
IEEE Annals of the History of Computing
Science in Context
Publishers
Duke University Press
Cambridge University Press
Armando
Cold Spring Harbor Laboratory Press
Columbia University Press
Donzelli
Concepts
Biology
Molecular biology
Genetics
Epigenetics
DNA; RNA
Synthetic biology; bioengineering
People
Waddington, Conrad Hal
Crick, Francis
Lederberg, Joshua
Loeb, Jacques
Feigenbaum, Edward Albert
Anna Dumitriu
Time Periods
21st century
20th century
20th century, late
19th century
Places
Edinburgh (Scotland)
Institutions
Human Genome Project
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