This thesis is a historical study of peptic ulcer disease from the sixth decade of the 1760-2000eighteenth century until the end of the twentieth. Symptoms of dyspepsia or indigestion have affected more than twenty percent of the British population for most of that period and attracted the involvement of many medical practitioners and others with the provision of health care. Within this group of symptomatic dyspeptic patients were to be found gastric and duodenal ulcers which were capable of causing serious health problems. However the prevalence of stomach and duodenal peptic ulcers has declined markedly during the time course of this thesis and now they are relatively uncommon. Although peptic ulcers may still have a fatal outcome, they now are considered to be curable conditions for the majority of patients who suffer from them in the developed world. This thematic history of gastric and duodenal ulcer examines how medical practitioners worked in a changing climate of novel ideas about disease, often aided or driven by technological developments, from the nineteenth century onwards. It begins with a humoural approach to the understanding of disease, which concentrated upon a patient¿s personality, lifestyle choices and circumstances but this was gradually displaced from the end of the eighteenth century by the clinico-anatomical approach, which sought to identify a specific lesion as the `seat¿ of the disease. In the nineteenth century, the discoveries of pathology, physiology, chemistry and bacteriology became incorporated in clinical medical practice, involving the laboratory in the investigation and treatment of many diseases. In the twentieth century, medical research became rooted in experimentation using scientific technology and engineering to equip investigators with new methods which changed the ways in which diseases were understood and treated. Although there were many innovations in theoretical concepts of disease aetiology and empirical treatments, many were subsequently rejected for reasons of ineffectiveness or possible harm to the patient, sometimes after long periods of use. In its first part, the thesis draws upon publications from 1769 until 1950, mostly in the form of scientific articles and books. In the second part, the oral testimonies of health care professionals involved with the management and treatment of gastric and duodenal ulcers are added. The recorded testimonies of 28 witnesses have been preserved in written form as a supplement to this dissertation. The history of peptic ulcer disease over the past two hundred years as described in this thesis follows a broadly similar course to that of other diseases such as tuberculosis, syphilis and chronic renal disease which once dominated the lives of those who suffered from them and have largely become curable in recent years. This thesis is offered as an account of an equally fascinating and complex disease. ]]>
...MoreDescription Defense date not indicated; cited by UMI in 2014. Defense date not indicated; cited by UMI in 2014. Cited in ProQuest, UMI Dissertations Publishing. Proquest Document ID: 1557549125.
Article
Biddiss, Michael;
(2014)
Jane Austen (1775--1817) and the Cultural History of Health
(/isis/citation/CBB001421985/)
Thesis
Jones, David Shumway;
(2001)
Rationalizing epidemics: Historical accounts of American Indian health disparities
(/isis/citation/CBB001562613/)
Book
David Gentilcore;
Matthew Smith;
(2018)
Proteins, Pathologies and Politics: Dietary Innovation and Disease from the Nineteenth Century
(/isis/citation/CBB880825514/)
Book
Floud, Roderick;
(2011)
The Changing Body: Health, Nutrition, and Human Development in the Western World since 1700
(/isis/citation/CBB001320093/)
Book
Martha Few;
(2015)
For All of Humanity: Mesoamerican and Colonial Medicine in Enlightenment Guatemala
(/isis/citation/CBB029842103/)
Article
Julia Wells;
(2018)
"I Was Doctor": White Settler Women's Amateur Medical Practice in East and South-Central African Communities, 1890–1939
(/isis/citation/CBB591035348/)
Chapter
Shelley W. Chan;
(2016)
Narrating Cancer, Disabilities, and aids: Yan Lianke’s Trilogy of Disease
(/isis/citation/CBB974132031/)
Book
Blom, Ida;
(2012)
Medicine, Morality, and Political Culture: Legislation on Venereal Disease in Five Northern European Countries, c.1870--c.1995
(/isis/citation/CBB001214602/)
Book
Wrigley, Richard;
Revill, George;
(2000)
Pathologies of Travel
(/isis/citation/CBB000110604/)
Article
Jennings, Michael;
(2002)
“This Mysterious and Intangible Enemy”: Health and Disease amongst the Early UMCA Missionaries, 1860-1918
(/isis/citation/CBB000200023/)
Thesis
William John Ryan;
(2015)
"A New Strange Disease": Atlantic Medicine, Affective History, and the Novel in America; 1690-1800
(/isis/citation/CBB356288858/)
Book
Tim Carter;
(2014)
Merchant Seamen's Health, 1860-1960: Medicine, Technology, Shipowners and the State in Britain
(/isis/citation/CBB510390199/)
Book
Phillips, Howard;
(2012)
Epidemics: The Story of South Africa's Five Most Lethal Human Diseases
(/isis/citation/CBB001421023/)
Book
Naoë Kukita Yoshikawa;
(2015)
Medicine, Religion and Gender in Medieval Culture
(/isis/citation/CBB323793152/)
Article
Keiko Daidoji;
(2018)
The Formation of Constitutional (Taishitsu) Medicine in Early Twentieth-Century Japan:The Scrofulous Constitution (Senbyōshitsu) and Tuberculosis
(/isis/citation/CBB189971009/)
Book
Hamlin, Christopher S.;
(2014)
More Than Hot: A Short History of Fever
(/isis/citation/CBB001510060/)
Book
Lise Dumasy-Queffélec;
Hélène Spengler;
(2014)
Médecine, sciences de la vie et littérature en France et en Europe de la révolution à nos jours
(/isis/citation/CBB263680135/)
Book
Dinges, Martin;
Barras, Vincent;
(2007)
Krankheit in Briefen im deutschen und französischen Sprachraum: 17.--21. Jahrhundert
(/isis/citation/CBB000950237/)
Article
Bartosz Michał Radomski;
Dunja Šešelja;
Kim Naumann;
(2021)
Rethinking the history of peptic ulcer disease and its relevance for network epistemology
(/isis/citation/CBB749209066/)
Book
Blécourt, Willem de;
Usborne, Cornelie;
(2004)
Cultural Approaches to the History of Medicine: Mediating Medicine in Early Modern and Modern Europe
(/isis/citation/CBB000772152/)
Be the first to comment!