IsisCB Explore

Thesis ID: CBB001567417

Fighting Polio: Selling the Gamma Globulin Field Trials, 1950--1953 (cited 2012)

University of Cambridge (United Kingdom)
Cambridge University

Outside Links

Academia.edu

Experimental medicine Clinical trials Poliomyelitis Vaccines; vaccination Hematology Placebo Public health 20th century United States Roosevelt, Franklin D.

Connor, sponsored an audacious human medical experiment. Led by University of Pittsburgh polio researcher Dr William McD. Hammon, the field test of a human blood fraction known as gamma globulin marked the first time that a large placebo-controlled clinical trial was conducted on healthy civilian children in American history. By drawing on private institutional records, scientific meeting minutes, oral histories, and historical newspapers, this dissertation explores the ethics and marketing of the experiment from its inception to its conclusion and the subsequent national inoculation program in 1953. Although the study, conducted in select areas of Utah, Texas and Iowa, was a marketing success that tested the boundaries of what civilians would tolerate in a moment of crisis, it was a scientific and ethical failure that harboured a range of adverse reactions. For Hammon and his allies, maintaining the perception of scientific progress in the war against the fearsome specter of polio emerged as a vital rationale to persist with the study and defend its aftermath. ]]>

...More

Description Defense date not indicated; cited by UMI in 2012. Cited in ProQuest, UMI Dissertations Publishing. Proquest Document ID: 1442475246.

Citation URI

https://data.isiscb.org/isis/citation/CBB001567417/

Citations Indexes

Similar Citations

Book Kathryn T. Hall; (2022)
Placebos (/isis/citation/CBB774087923/)

Book Jacobs, Charlotte; (2015)
Jonas Salk: A Life (/isis/citation/CBB001422650/)

Book Conis, Elena; (2014)
Vaccine Nation: America's Changing Relationship with Immunization (/isis/citation/CBB001422034/)

Article David Teira; (2019)
Placebo trials without mechanisms: How far can they go? (/isis/citation/CBB058338660/)

Book Porras Gallo, María Isabel; María Isabel / Báguena Cervellera, María José / Ayarzagüena Sanz, Mariano / Martín Espinosa, Noelia María Porras Gallo; Ayarzagüena Sanz, Mariano; Noelia María Martín Espinosa; (2016)
La erradicación y el control de las enfermedades infecciosas (/isis/citation/CBB703301554/)

Article Axelsson, Per; (2012)
The Cutter Incident and the Development of a Swedish Polio Vaccine, 1952--1957 (/isis/citation/CBB001211096/)

Article Fantini, Bernardino; (2012)
Polio in Italy (/isis/citation/CBB001211097/)

Book Wilson, Daniel J.; (2009)
Polio (/isis/citation/CBB001031562/)

Article Day, Alison; (2009)
“An American Tragedy”. The Cutter Incident and Its Implications for the Salk Polio Vaccine in New Zealand, 1955--1960 (/isis/citation/CBB001232089/)

Article Vargha, Dora; (2014)
Between East and West: Polio Vaccination across the Iron Curtain in Cold War Hungary (/isis/citation/CBB001420184/)

Article Ballester, R.; Porras, M-I; (2009)
El significado histórico de las encuestas de seroprevalencia como tecnología de laboratorio aplicada a las campañas de inmunización. El caso de la poliomielitis en España (/isis/citation/CBB000931887/)

Book Gareth Millward; (2019)
Vaccinating Britain: Mass vaccination and the public since the Second World War (/isis/citation/CBB045417876/)

Book Paolo Leoncini; Paolo Neri; (2022)
La guerra dei vaccini. Cosa può insegnare la vicenda di Albert. B. Sabin (/isis/citation/CBB232441840/)

Article Tara Suri; (2022)
Between Simians and Cell Lines: Rhesus Monkeys, Polio Research, and the Geopolitics of Tissue Culture (1934–1954) (/isis/citation/CBB316653885/)

Book Oshinsky, David M.; (2005)
Polio: An American Story (/isis/citation/CBB000641645/)

Thesis Ward, Susan Mechele; (2005)
Rhetorically Constructing a “Cure”: FDR's Dynamic Spectacle of Normalcy (/isis/citation/CBB001561803/)

Chapter Christopher Crenner; (2017)
Placebos and the Progress of Surgery (/isis/citation/CBB552034486/)

Article Fairchild, Amy L.; (2001)
The Polio Narratives: Dialogues with FDR (/isis/citation/CBB000100881/)

Article Rodríguez Sánchez, J. A.; Seco Calvo, J.; (2009)
Las campañas de vacunación contra la poliomielitis en España en 1963 (/isis/citation/CBB000931888/)

Article Baptiste Baylac-Paouly; (2019)
Vaccine development as a ‘doable problem’: The case of the meningococcal A vaccines 1962–1969 (/isis/citation/CBB049448868/)

Comments

{{ comment.created_by.username }} on {{ comment.created_on | date:'medium' }}