Article ID: CBB001451245

The Long and Winding Road of Molecular Data in Phylogenetic Analysis (2014)

unapi

The use of molecules and reactions as evidence, markers and/or traits for evolutionary processes has a history more than a century long. Molecules have been used in studies of intra-specific variation and studies of similarity among species that do not necessarily result in the analysis of phylogenetic relations. Promoters of the use of molecular data have sustained the need for quantification as the main argument to make use of them. Moreover, quantification has allowed intensive statistical analysis, as a condition and a product of increasing automation. All of these analyses are subject to the methodological anxiety characteristic of a community in search of objectivity (Suárez-Díaz and Anaya-Muñoz, Stud Hist Philos Biol Biomed Sci 39:451-458, 2008 ). It is in this context that scientists compared and evaluated protein and nucleic acid sequence data with other types of molecular data - including immunological, electrophoretic and hybridization data. This paper argues that by looking at long-term historical processes, such as the use of molecular evidence in evolutionary biology, we gain valuable insights into the history of science. In that sense, it accompanies a growing concern among historians for big-pictures of science that incorporate the fruitful historical research on local cases of the last decades.[PUBLICATION ABSTRACT]

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Authors & Contributors
Méthot, Pierre-Olivier
Henri Buc
Hall, Kersten T.
Zimmer, Karl Günter
Yamashita, Grant Joo
Winnie, John A.
Concepts
Molecular biology
Biology
Evolution
Genetics
Philosophy of biology
Darwinism
Time Periods
20th century
19th century
18th century
20th century, late
Ancient
20th century, early
Places
United States
Europe
Institutions
Collège de France, Paris
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