Fagan, Melinda Bonnie (Author)
Examining stem cell biology from a philosophy of science perspective, this book clarifies the field's central concept, the stem cell, as well as its aims, methods, models, explanations and evidential challenges. The first chapters discuss what stem cells are, how experiments identify them, and why these two issues cannot be completely separated. The basic concepts, methods and structure of the field are set out, as well as key limitations and challenges. The second part of the book shows how rigorous explanations emerge from stem cell experiments, and compares these to other kinds of scientific explanation. Model organisms, the role of genes, and the significance of collaboration are also discussed. The last part of the book considers relations to systems biology and clinical medicine, arguing that both the mathematical models of the former, and ethical principles of the latter, are necessary for stem cell biology to deliver on its promises.
...MoreReview Stavros Ioannidis (2015) Review of "Philosophy of Stem Cell Biology: Knowledge in Flesh and Blood". Metascience: An International Review Journal for the History, Philosophy and Social Studies of Science (pp. 285-288).
Review Germain, Pierre-Luc (2014) Review of "Philosophy of Stem Cell Biology: Knowledge in Flesh and Blood". History and Philosophy of the Life Sciences (pp. 146-148).
Review O'Malley, Maureen A. (2014) Review of "Philosophy of Stem Cell Biology: Knowledge in Flesh and Blood". Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences (p. 149).
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