Article ID: CBB001320665

Estimating F-Statistics: A Historical View (2012)

unapi

Characterizing the genetic structure of populations is of importance to evolutionary biology, to human disease gene mapping, and to forensic science. Sewall Wright introduced a set of F-statistics to describe population structure in 1951, and he emphasized that these quantities were ratios of variances. Responding to uncertainty over the best way to estimate F-statistics, Weir and Cockerham published a method-of-moments set of estimators in 1984. This paper continues to be widely cited, with over 7,000 citations to date. Some background to the publishing history of the Weir and Cockerham paper is given here, along with subsequent developments and a discussion of current uses of Wright's F-statistics.

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Authors & Contributors
Hogan, Andrew J.
Gravlee, Clarence C.
Montoya, Michael J.
Navon, Daniel
Jordan, Bertrand
Sheldon, Myrna Lynn Perez
Journals
Social Studies of Science
Science
Endeavour: Review of the Progress of Science
Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences
Science, Technology and Human Values
Perspectives in Biology and Medicine
Publishers
University of California, Riverside
University of California, Santa Barbara
Johns Hopkins University Press
Edizioni ETS
Ashgate
University of Minnesota
Concepts
Genetics
Genetic diseases and disorders
Forensic sciences
Biology and ethics; bioethics
Human genetics
DNA; RNA
People
Rose, Nicholas
Müller, Hermann Joseph
Sokal, Robert R.
Gould, Stephen Jay
Glass, Bentley
Britten, Roy J.
Time Periods
20th century, late
21st century
20th century
20th century, early
Places
United States
Italy
Mexico
Institutions
Human Genome Project
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