Article ID: CBB001252559

LSD: Catalyst for a Pharmacological Revolution (2006)


Albert Hofmann's discovery of LSD by chance or by a higher plan led to a revolution in the pharmaceutical industry, inspiring research to understand how a chemical's structure is recognized and how this recognition triggers a physiological response. The incredible potency of this drug challenged the conventional lock-and-key model that Emil Fischer had proposed for enzymes. In fact, the astounding physiological properties of LSD may have overshadowed the scientific expertise and outstanding qualities of its discoverer, Albert Hofmann, who celebrated his 100th birthday this year. The first article in this series (pp 413-420) sketches Hofmann's discovery of LSD, its use as an adjunct to meditation, creativity, and consciousness expansion, and treatment of the mentally ill as well as its abuse as a pleasure drug. The third article (pp 427-436) discusses Hofmann's life and especially his chemistry and his passion for nature. We are also reviewing a Festschrift commemorating his centenary (pp 451-452).

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Authors & Contributors
Oram, Matthew
Pieters, Toine
Kauffman, George B.
Craig, G. Wayne
Montagne, Michael
Domínguez Vilaplana, Rafaela
Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences
Pharmacy in History
The Chemical Educator
Llull: Revista de la Sociedad Española de Historia de las Ciencias y de las Técnicas
Journal of the History of Medicine and Allied Sciences
Istoriko-Biologicheskie Issledovaniia
Rutgers, the State University of New Jersey, New Brunswick
The MIT Press
Johns Hopkins University Press
University of Manitoba Press
Purdue University (Lafayette, Indiana)
University of Minnesota Press
Psychotropic drugs
LSD (drug)
Pharmaceutical industry
Hofmann, Albert
Woolley, Dilworth Wayne
Time Periods
20th century, late
20th century
20th century, early
19th century
21st century
United States
Saskatchewan (Canada)
Saskatchewan Hospital
Purdue University (Lafayette, Indiana)

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