Article ID: CBB001221584

Re-Thinking Organisms: The Impact of Databases on Model Organism Biology (2012)

unapi

Leonelli, Sabina (Author)
Ankeny, Rachel A. (Author)


Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences
Volume: 43
Pages: 29--36


Publication Date: 2012
Edition Details: Part of a special section: “Data-Driven Research in the Biological and Biomedical Sciences”
Language: English

Community databases have become crucial to the collection, ordering and retrieval of data gathered on model organisms, as well as to the ways in which these data are interpreted and used across a range of research contexts. This paper analyses the impact of community databases on research practices in model organism biology by focusing on the history and current use of four community databases: FlyBase, Mouse Genome Informatics, WormBase and The Arabidopsis Information Resource. We discuss the standards used by the curators of these databases for what counts as reliable evidence, acceptable terminology, appropriate experimental set-ups and adequate materials (e.g., specimens). On the one hand, these choices are informed by the collaborative research ethos characterising most model organism communities. On the other hand, the deployment of these standards in databases reinforces this ethos and gives it concrete and precise instantiations by shaping the skills, practices, values and background knowledge required of the database users. We conclude that the increasing reliance on community databases as vehicles to circulate data is having a major impact on how researchers conduct and communicate their research, which affects how they understand the biology of model organisms and its relation to the biology of other species.

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Article Leonelli, S. (2012) Introduction: Making Sense of Data-Driven Research in the Biological and Biomedical Sciences. Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences (p. 1). unapi

Citation URI
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Authors & Contributors
Stevens, Hallam
Goëta, Samuel
Denis, Jérôme
Wennerström, Frida
Soyer, Orkun S.
Sepkoski, David Christopher
Concepts
Bioinformatics
Data analysis
Biology
Computers and computing
Databases
Experimental organisms
Time Periods
20th century, late
21st century
20th century
19th century
20th century, early
Places
Great Britain
United States
South Africa
France
Institutions
Cambridge. University. Laboratory of Molecular Biology
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