Article ID: CBB001213878

A Short History of the Notion of Neurodegenerative Disease (2014)

unapi

The notion of heredity of degenerative constitutions of human beings contributed in the nineteenth century to the fear for deterioration of the human race and in the twentieth century to attempts by several Western Countries, particularly Germany, to improve the inborn qualities of their populations by eugenic measures. In the years following World War II, the term eugenics was eradicated from medicine. The qualification degenerative disappeared from genetics and psychiatry but remained in use to denote decay of tissues and cells. The adjective neurodegenerative came in vogue in neurology and was mostly applied to brain diseases. Definitions in the literature indicate that neurodegenerative diseases are considered as to be age related, incurable, and largely untreatable chronic progressive diseases of the central nervous system. Scrutiny of available data shows that the notion concerns an ill-defined group of genetic and idiopathic disorders. Genetic central nervous system diseases may become manifest at all ages and are accessible for symptomatic treatment. Investigations of animal models suggest that not all neurodegenerative diseases are inherently incurable. Alternatives for the terms neurodegenerative and degenerative are available.

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Authors & Contributors
Binder, Devin K.
Boling, Warren W.
Brenninkmeijer, Jonna
Brosius, Stephanie
Bruyn, George W.
Eadie, Mervyn J.
Journals
Journal of the History of the Neurosciences
History and Philosophy of the Life Sciences
History of the Human Sciences
Journal of the History of Medicine and Allied Sciences
Taiwan shehui yanjiu jikan (Taiwan: A Radical Quarterly in Social Studies)
Medicina Historica
Publishers
Boom
MIT Press
New York University Press
Concepts
Neurology
Neurological diseases
Neurosciences
Medicine
Disease and diseases
Epilepsy
People
Charcot, Jean Martin
Duchenne de Boulogne, Guillaume Benjamin
Economo, Constantin von
Hoppe, Herman
Kanzō, Uchimura
Marie, Pierre
Time Periods
19th century
20th century, early
20th century, late
21st century
18th century
20th century
Places
France
Persia (Iran)
Taiwan
Germany
Greece
Italy
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