Article ID: CBB001213636

Genome: Twisting Stories with DNA (2013)

unapi

In 1920, the German botanist Hans Winkler coined the concept of the `genome'. This paper explores the history of a concept that has developed in parallel with advances in biology and supports novel and powerful heuristic biological research in the 21st century. From a structural interpretation (the genome as the haploid number of chromosomes), it has changed to keep pace with technological progress and new interpretations of the material of heredity. In the first place, the `genome' was extended to include all the material in the nucleus, then the sum of all genes, and (with the discovery of the structure of DNA) the sum of the nucleotide base sequences. In the early 21st century, it has become a much more complex and central concept that has spawned the growing field of studies referred to as the `omics'.

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Authors & Contributors
Minelli, Alessandro
Holmes, Tarquin
Silberstein, Marc
Lambert, Gérard
Buiatti, Marcello
Tudge, Colin
Concepts
Biology
Genetics
Genes
Research
Evolution
Heredity
Time Periods
20th century
21st century
19th century
20th century, late
18th century
Places
United States
Russia
Italy
Canada
Soviet Union
Great Britain
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