Book ID: CBB001213249

The Philadelphia Chromosome: A Mutant Gene and the Quest to Cure Cancer at the Genetic Level (2013)


Wapner, Jessica (Author)

The Experiment, LLC

Publication Date: 2013
Physical Details: xiii + 303 pp.; ill.
Language: English

This work discusses the history of a genetic mutation, discovered in 1959, that causes chronic myeloid leukemia, and traces the research and breakthroughs that led to the creation of a drug that makes this once-fatal illness now treatable. It focuses on what is widely viewed as the 'poster child' of rational drug development in the cancer research world. The history of the founding of a genetic mutant chromosome in the indication of Chronic myeloid leukemia disease, and the subsequent development of "Gleevec," is the keynote of this publication.

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Authors & Contributors
Dietmar Steverding
Weatherall, David
Timmermann, Carsten
Thagard, Paul R.
Santesmases, María Jesús
Ross, Malcom
Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences
Studies in History and Philosophy of Science
Social History of Medicine
Signs: Journal of Women in Culture and Society
Naturwissenschaftliche Rundschau
Rowman & Littlefield
Oxford University Press
Auckland University Press
Yale University
Disease and diseases
Cancer; tumors
Medical genetics
Miller, Oscar R.
Lewontin, Richard C.
Delbrück, Max
Time Periods
20th century, late
21st century
20th century
United States
New Zealand
National Institute of Health (U.S.)

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