Book ID: CBB001212053

Crucible of Science: The Story of the Cori Laboratory (2013)

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Exton, John H. (Author)


Oxford University Press


Publication Date: 2013
Physical Details: xvi + 226 pp.; ill.
Language: English

Publisher: "Crucible of Science" is the story of a unique laboratory at Washington University in St. Louis, and of Carl and Gerty Cori, the biochemists who established it. Carl and Gerty met and married at medical school in Prague in the 1920s. After graduation, they immigrated to the U.S. to escape deteriorating conditions in Europe. Carl soon received an offer from Washington University to become Pharmacology Chair, and the couple settled in St. Louis. Not only did both Coris go on to win the Nobel Prize, the laboratory they established at the University has since produced some of the most outstanding scientists the U.S. has ever seen. Six laboratory scientists also won Nobel Prizes; few, if any, laboratories can claim such an impressive record. The Coris themselves were instrumental in establishing the then new science of Biochemistry in the U.S. They applied chemical approaches to elucidating the transformations of compounds such as glucose in animal tissues and defined the enzyme catalysts that carried out those transformations. Both scientists were extremely rigorous in designing their experiments and interpreting the results, a habit that ensured their findings were above question. This book examines the careers of both Coris and the other eminent scientists who trained in their laboratory. It notes the Coris' acceptance of women, Jews, and scientists from all over the world, unique during this time period. It analyzes those reasons why the laboratory was so successful in attracting the best trainees and producing premier scientists. Intended for scientists, science historians, and anyone interested in the history of science, "Crucible of Science" is a unique presentation of remarkable careers and personalities, examined within the context of the Coris' laboratory.

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Description On the biochemistry laboratory which has hosted many eminent scientists.


Citation URI
https://data.isiscb.org/isis/citation/CBB001212053/

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Authors & Contributors
Cohn, Mildred
Fisher, Linda A.
Goedeke, T. L.
Grubb, Robert L
Harper, Christine Froechtenigt
Heathcott, Joseph
Journals
Missouri Historical Review
Earth Sciences History: Journal of the History of the Earth Sciences Society
History and Philosophy of the Life Sciences
Journal of Biosciences
Journal of Design History
Journal of the History of Medicine and Allied Sciences
Publishers
American Mathematical Society
CRC Press
Facts on File
Indiana University Press
Northern Illinois University Press
University of Illinois Press
Concepts
Biographies
Railroads
Land transportation
Natural history
Development of science; change in science
Biochemistry
People
Cori, Carl Ferdinand
Cori, Gerty Theresa
Flexner, Abraham
Haurowitz, Felix
Trotter, Mildred
Houck, Lewis
Time Periods
19th century
20th century
20th century, early
18th century
20th century, late
21st century
Places
United States
Missouri (U.S.)
St. Louis (Missouri, U.S.)
Illinois (U.S.)
Austria
Oklahoma (U.S.)
Institutions
Washington University in St. Louis
Washington University (St. Louis, Missouri)
Missouri Pacific Railroad Company
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