This article explores the conceptual tools which philosopher, sociologist and anthropologist Bruno Latour uses to understand and also to explain natural and social realities investigated by the sciences and by the philosophy of science. This text also sets the limits to Labour's principle of radical indeterminacy, also known as the principle of generalized symmetry. As a result of this, the possibility of a normative study of social and techno-scientific realities is emphasized as a type of technoscientific and social research, which is compatible with Labour's own evolution of thought concerning the meaning and function of the politics of science. Keywords: radical indeterminacy, actors, a-modernity, normativity, expertise, legitimacy.
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