This article describes the sustained effort by American researchers between the mid-1930s and the mid-1950s to develop an effective influenza vaccine. From almost the beginning of this project, researchers succeeded in protecting laboratory animals from lethal influenza infection, and they believed that success with humans would follow quickly. Yet although they succeeded in producing a vaccine that proved effective in field trials in 1943 and 1945, that same vaccine failed to offer any protection in 1947. This vaccine failure forced researchers to reconsider the growing evidence of antigenic variation and challenged the model of the virus that had been taken for granted.
...MoreDescription On the “effort by American researchers between the mid-1930s and the mid-1950s to develop an effective influenza vaccine.” (from the abstract)
Article
Dicke, Tom;
(2015)
Waiting for the Flu: Cognitive Inertia and the Spanish Influenza Pandemic of 1918--19
(/isis/citation/CBB001551156/)
Book
Barry, John M.;
(2004)
The Great Influenza: The Epic Story of the Deadliest Plague in History
(/isis/citation/CBB000470031/)
Book
Willrich, Michael;
(2011)
Pox: An American History
(/isis/citation/CBB001212485/)
Article
Levina, Elena S.;
(2010)
The First Virologists and the Medical Virology in the USSR, 1930s
(/isis/citation/CBB001421106/)
Book
Jacobs, Charlotte;
(2015)
Jonas Salk: A Life
(/isis/citation/CBB001422650/)
Article
Bresalier, Michael;
(2013)
Fighting Flu: Military Pathology, Vaccines, and the Conflicted Identity of the 1918--19 Pandemic in Britain
(/isis/citation/CBB001252196/)
Article
Eyler, John M.;
(2009)
The Fog of Research: Influenza Vaccine Trials during the 1918--19 Pandemic
(/isis/citation/CBB000932685/)
Book
Offit, Paul A.;
(2005)
The Cutter Incident: How America's First Polio Vaccine Led to the Growing Vaccine Crisis
(/isis/citation/CBB000650682/)
Article
Gregory J. Higby;
(2020)
Visual Pharmacy: “Pe-Ru-Na for Spanish Influenza”
(/isis/citation/CBB570958789/)
Article
Jahn, Stefanie;
(2014)
Die Grippe-Pandemie nach dem Ersten Weltkrieg und die Homöopathie im internationalen Vergleich
(/isis/citation/CBB001421921/)
Thesis
Méthot, P-O.;
(cited 2012)
Historical Epistemology of the Concept of Virulence: Molecular, Ecological, and Evolutionary Perspectives on Emerging Infectious Disease in the 19th and 20th Century
(/isis/citation/CBB001567416/)
Book
Eckart, Wolfgang Uwe;
(2014)
Medizin und Krieg: Deutschland 1914--1924
(/isis/citation/CBB001451910/)
Article
Serrón, Víctor;
(2011)
Epidemia y perplejidades médicas: Uruguay, 1918--1919
(/isis/citation/CBB001420534/)
Article
Almeida, Maria Antónia Pires de;
(2013)
Epidemics in the News: Health and Hygiene in the Press in Periods of Crisis
(/isis/citation/CBB001320417/)
Book
Kolata, Gina Bari;
(1999)
Flu: The story of the great influenza pandemic of 1918 and the search for the virus that caused it
(/isis/citation/CBB000111978/)
Book
Humphries, Mark Osborne;
(2013)
The Last Plague: Spanish Influenza and the Politics of Public Health in Canada
(/isis/citation/CBB001420164/)
Book
Fabio Montella;
(2022)
La spagnola. Storie e cronaca della pandemia influenzale del 1918
(/isis/citation/CBB745179403/)
Article
Seyyed Alireza Golshani;
Babak Daneshfard;
Seyed Amir Hossein Golshani;
Mohammad Ebrahim Zohalinezhad;
(2023)
Spanish Flu in Shiraz from 1918 to 1920
(/isis/citation/CBB468425569/)
Article
Simmons, David;
(2009)
Religion and Medicine at the Crossroads: A Re-Examination of the Southern Rhodesian Influenza Epidemic of 1918
(/isis/citation/CBB001031036/)
Book
Fanning, Patricia J.;
(2010)
Influenza and Inequality: One Town's Tragic Response to the Great Epidemic of 1918
(/isis/citation/CBB001212737/)
Be the first to comment!