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Article ID: CBB000773208

Medical Statistics and Hospital Medicine: The Case of the Smallpox Vaccination (2007)

Centaurus: International Magazine of the History of Mathematics, Science, and Technology
Volume: 49
Pages: 337--359

Publication Date: 2007
Edition Details: Part of the special issue: “The Statistical Office as a Social Observatory”
Language: English

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Medicine Vaccines; vaccination Clinical trials Medical statistics Smallpox Probability and statistics Empiricism 18th century

Between 1799 and 1806, trials of vaccination to determine its safety and efficacy were undertaken in hospitals in London, Paris, Vienna, and Boston. These trials were among the first instances of formal hospital evaluations of a medical procedure and signal a growing acceptance of a relatively new approach to medical practice. These early evaluations of smallpox vaccination also relied on descriptive and quantitative accounts, as well as probabilistic analyses, and thus occupy a significant, yet hitherto unexamined, place in the history of medical statistics.

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Article Porter, Theodore M. (2007) Introduction. Centaurus: International Magazine of the History of Mathematics, Science, and Technology (p. 258). unapi

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https://data.isiscb.org/isis/citation/CBB000773208/

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