Darden, Lindley (Author)
Philosophers have proposed various kinds of relations between Mendelian genetics and molecular biology: reduction, replacement, explanatory extension. This paper argues that the two fields are best characterized as investigating different, serially integrated, hereditary mechanisms. The mechanisms operate at different times and contain different working entities. The working entities of the mechanisms of Mendelian heredity are chromosomes, whose movements serve to segregate alleles and independently assort genes in different linkage groups. The working entities of numerous mechanisms of molecular biology are larger and smaller segments of DNA plus related molecules. Discovery of molecular DNA mechanisms filled black boxes that were noted, but unilluminated, by Mendelian genetics.
...MoreArticle Craver, Carl F.; Darden, Lindley (2005) Introduction. Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences (p. 233).
Book
Gissis, Snait B.;
Jablonka, Eva;
(2011)
Transformations of Lamarckism: From Subtle Fluids to Molecular Biology
(/isis/citation/CBB001500079/)
Thesis
Valerie Racine;
(2016)
Beyond Reductionism and Emergence: A Study of the Epistemic Practices in Gene Expression Research
(/isis/citation/CBB978842577/)
Book
Rheinberger, Hans-Jörg;
(2010)
An Epistemology of the Concrete
(/isis/citation/CBB001023158/)
Article
Harman, Oren Solomon;
(2006)
Method as a Function of “Disciplinary Landscape”: C.D. Darlington and Cytology, Genetics and Evolution, 1932--1950
(/isis/citation/CBB000670096/)
Chapter
Gissis, Snait B.;
Jablonka, Eva;
(2011)
The Exclusion of Soft (“Lamarckian”) Inheritance from the Modern Synthesis
(/isis/citation/CBB001500089/)
Article
Loison, Laurent;
(2011)
French Roots of French Neo-Lamarckisms, 1879--1985
(/isis/citation/CBB001220959/)
Article
Alan Grafen;
(2019)
Should we ask for more than consistency of Darwinism with Mendelism?
(/isis/citation/CBB453166142/)
Book
Hull, David L.;
(2001)
Science and Selection: Essays on Biological Evolution and the Philosophy of Science
(/isis/citation/CBB000100243/)
Essay Review
Griffiths, Paul E.;
(2002)
Lost: One Gene Concept. Reward to Finder
(/isis/citation/CBB000200474/)
Article
Winnie, John;
(2000)
Information and structure in molecular biology: Comments on Maynard Smith
(/isis/citation/CBB000110641/)
Book
Ruse, Michael;
Travis, Joseph;
(2009)
Evolution: The First Four Billion Years
(/isis/citation/CBB001232307/)
Book
Burian, Richard M.;
(2005)
The Epistemology of Development, Evolution, and Genetics: Selected Essays
(/isis/citation/CBB000550822/)
Article
Tarquin Holmes;
(2017)
The wild type as concept and in experimental practice: A history of its role in classical genetics and evolutionary theory
(/isis/citation/CBB016897194/)
Book
Brzezinski Prestes, Maria Elice;
Martins, Lilian Al-Chueyr Pereira;
Stefano, Waldir;
(2006)
Filosofia e História da Biologia 1
(/isis/citation/CBB000820181/)
Article
Davies, Paul Sheldon;
(2000)
Malfunctions
(/isis/citation/CBB000111900/)
Article
Sterelny, Kim;
(2000)
The “Genetic Program” Program: A commentary on Maynard Smith on Information in Biology
(/isis/citation/CBB000110644/)
Article
Smith, John Maynard;
(2000)
The Concept of Information in Biology
(/isis/citation/CBB000110643/)
Article
Brenner, Sydney;
(2012)
The Revolution in the Life Sciences
(/isis/citation/CBB001320451/)
Article
Harman, Oren;
(2003)
Darlington and the “Invention” of the Chromosome
(/isis/citation/CBB000600546/)
Article
Santesmases, María Jesús;
(2013)
The Biological Landscape of Polyploidy: Chromosomes under Glass in the 1950s
(/isis/citation/CBB001211941/)
Be the first to comment!