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Article ID: CBB000057685

The history of a controversy over the role of inorganic iron in the treatment of anemia (1990)

Carpenter, Kenneth J. (Author)

Journal of Nutrition
Volume: 120
Pages: 141-147

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Description “It was not unexpected ... that from 1850 on into the next century large dietary supplements of iron salts were reported to be almost (or entirely) indigestible. Yet iron salts were undoubtedly effective in treating simple anemia. To escape from the paradox, it was argued that iron salts combined with hydrogen sulfide in the gut, thus sparing the natural organic iron of the diet and allowing it to be better absorbed. Despite experiments refuting this hypothesis, the belief that inorganic iron could not be used in hemoglobin synthesis lingered into the 1920s.” From the abstract.

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